Zidovudine (oral/injection)

Zidovudine is an antiviral medicine made use of to deal with HIV, the virus that can create acquired immunodeficiency syndrome (AIDS). Zidovudine is additionally offered during pregnancy to avoid an HIV-infected female from passing the infection to her child. Zidovudine is not a cure for HIV or AIDS.

Zidovudine may also be utilized for functions not provided in this drug overview.

You may create lactic acidosis, a dangerous accumulation of lactic acid in your blood. Get emergency clinical assistance if you have uncommon muscular tissue pain, trouble breathing, irregular heart beats, dizziness, throwing up, or if you really feel chilly, weary, or very weak.

Zidovudine can reduce blood cells that assist your body battle infections and help flow oxygen. Zidovudine can also create severe or lethal impacts on your liver.

Call your medical professional if you have symptoms such as: fever, flu signs and symptoms, uncommon fatigue, mouth sores, pale skin, chilly hands and feet, upper belly discomfort, dark pee, or jaundice (yellowing of the skin or eyes).

You must not utilize zidovudine if you dislike it.

You might establish lactic acidosis, a dangerous accumulation of lactic acid in your blood. This might be more probable if you have other medical conditions, if you've taken HIV medicine for a long period of time, or if you are a woman. Ask your medical professional concerning your risk.

Zidovudine can additionally trigger extreme or serious results on your liver. Inform your doctor if you have liver illness, specifically hepatitis C.

Tell your doctor if you have actually ever had:

• kidney condition;
• muscle issues;
• a latex allergy (if you receive zidovudine injection);.
• bone marrow reductions;.
• anemia (reduced red blood cells); or.
• if you consume big quantities of alcohol.

Inform your doctor if you are expectant, and utilize your medicines properly to regulate your infection. HIV can be passed to your baby if the virus is not regulated while pregnant. Your name might be detailed on a computer registry to track any effects of antiviral medication on the baby.

Ladies with HIV or AIDS should not bust feed an infant. Even if your infant is born without HIV, the virus might be passed to the baby in your bust milk.

Get emergency situation clinical help if you have indicators of an allergy (hives, tough breathing, swelling in your face or throat) or a severe skin reaction (high temperature, sore throat, burning in your eyes, skin pain, red or purple skin breakout that spreads out and triggers blistering and peeling).

Light signs and symptoms of lactic acidosis may worsen with time, and this condition can be fatal. Get emergency medical assistance if you have: uncommon muscle mass pain, problem breathing, tummy pain, vomiting, irregular heart price, wooziness, really feeling chilly, or sensation really weak or weary.

Zidovudine might cause significant adverse effects. Call your doctor at the same time if you have:

• low blood cell counts-- high temperature, cools, tiredness, mouth sores, skin sores, very easy bruising, uncommon bleeding, light skin, cold hands and feet, feeling light-headed or short of breath; or
• liver issues-- swelling around your waistline, right-sided upper belly discomfort, anorexia nervosa, dark pee, clay-colored stools, jaundice (yellowing of the skin or eyes).

Zidovudine affects your immune system, which may create specific negative effects (even weeks or months after you've made use of zidovudine). Inform your doctor if you have:

• signs of a new infection-- fever, evening sweats, inflamed glands, cold sores, cough, wheezing, looseness of the bowels, weight management;
• trouble talking or ingesting, problems with equilibrium or eye movement, weakness or irritable feeling; or
• swelling in your neck or throat (enlarged thyroid), menstruation modifications, erectile dysfunction.

Common adverse effects of zidovudine might include:

• headache;
• high temperature, basic sick sensation;
• coughing;
• queasiness, vomiting, loss of appetite; or
• loss of body fat (particularly in your arms, legs, face, and buttocks).

This is not a complete checklist of side effects and others might take place. Call your doctor for medical advice concerning adverse effects. You may report adverse effects to FDA at 1-800-FDA-1088.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Zidovudine oral is taken by mouth, usually in combination with other antiviral medications.

Zidovudine injection is given as an infusion into a vein. A healthcare provider will give you this injection if you are unable to take the medicine by mouth.

Zidovudine oral can be taken with or without food.

Measure liquid medicine carefully, especially when giving zidovudine to a baby. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Zidovudine doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.

Zidovudine can lower blood cells that help your body fight infections and help circulate oxygen in your body. You may get an infection or feel more tired than usual. Your blood will need to be tested often.

Use all HIV medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice. Every person with HIV should remain under the care of a doctor.

Store zidovudine oral at room temperature away from moisture and heat.

Take the medicine as soon as you can, but miss the missed out on dose if it is virtually time for your next dose. Do not take 2 doses at one time.

Due to the fact that you will receive zidovudine shot in a clinical setting, you are not most likely to miss a dosage.

Seek emergency medical focus or call the Poisonous substance Customer service at 1-800-222-1222.

Avoid alcohol consumption alcohol. It may increase your risk of liver damage or lactic acidosis.

Utilizing zidovudine will not prevent your disease from spreading. Talk with your medical professional regarding risk-free means to avoid HIV transmission throughout sex. Sharing medicine or medicine needles is never ever secure, even for a healthy and balanced individual.

Inform your physician about all your other medications, especially:

• doxorubicin;
• ribavirin;
• stavudine; or
• various other medicines which contains zidovudine (including mix medicines such as Combivir or Trizivir).

This checklist is not complete. Various other medicines might influence zidovudine, consisting of prescription and non-prescription medicines, vitamins, and natural items. Not all feasible medication interactions are detailed right here.