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Zinecard

Generic name: dexrazoxane

Last updated November 5, 2026 0 views
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What is Zinecard?

Zinecard is utilized to protect the heart and other cells from harmful side effects triggered by specific cancer drugs.

The Totect brand name of dexrazoxane is utilized in males or women to deal with a problem called extravasation (es-TRA-va-ZAY-shun). Extravasation happens when an injected medication leaves from the blood vessels and circulates into tissues in the body. Serious tissue damage can happen when extravasation occurs during shot of certain cancer drugs.

Zinecard is also used to help avoid chemotherapy-related heart issues in females that are obtaining doxorubicin for metastatic breast cancer. Zinecard is given just after you have gotten sufficient doxorubicin infusions to amount to a certain complete dosage.

Zinecard might additionally be utilized for functions not noted in this drug guide.

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Warnings

Zinecard can hurt an unborn infant or create abnormality if the mother or papa is making use of Zinecard. Tell your caregivers if you are expecting, or if you are a guy and your sex companion has the ability to get expectant.

You should not obtain Zinecard if your chemotherapy does not consist of doxorubicin or a similar medication (such as daunorubicin, epirubicin, idarubicin, or mitoxantrone).

Inform your doctor at once if you have indications of infection such as fever, cools, sore throat, simple bruising or bleeding, skin sores, or heat and inflammation of any kind of surgical cut.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You need to not receive Zinecard if your chemotherapy does not consist of doxorubicin or a comparable medication such as:

  • daunorubicin (Cerubidine, Daunoxome);.
  • epirubicin (Ellence);.
  • idarubicin (Idamycin); or.
  • mitoxantrone (Novantrone).

Inform your physician if you have actually ever had:.

  • heart issues;.
  • liver condition; or.
  • kidney condition.

Zinecard can hurt an expected baby or trigger birth defects if the mom or the daddy is obtaining this medicine. Ladies should utilize efficient contraception to stop maternity while receiving this medicine and for at the very least 6 months after the last dose. Guy should make use of birth control throughout treatment and for at least 3 months after the last dosage. Tell your physician today if a maternity occurs throughout this moment.

This medication might impact fertility (ability to have children) in men. However, it is very important to use birth control to avoid pregnancy because Zinecard might harm the infant if a maternity does happen.

You need to not breastfeed while you are making use of Zinecard. Females receiving Totect must continue to not breastfeed for a minimum of 2 weeks after the last dosage.

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Zinecard side effects

Obtain emergency clinical assistance if you have indicators of an allergy: hives; tough breathing; sensation light-headed; swelling of your face, lips, tongue, or throat.

Zinecard may trigger serious negative effects. Call your physician simultaneously if you have:

  • high temperature, cools, fatigue, mouth sores, skin sores;
  • very easy discoloration, unusual blood loss;
  • sore throat, cough, difficulty breathing; or
  • wounding, swelling, heat, soreness, exuding, or blood loss of any surgical incision.

Usual negative effects of Zinecard may consist of:

  • nausea, throwing up;
  • fever;
  • infection after a surgical procedure; or
  • discomfort where the medicine was infused.

This is not a complete checklist of side effects and others may happen. Call your physician for medical recommendations regarding negative effects. You might report adverse effects to FDA at 1-800-FDA-1088.

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How is Zinecard given?

Zinecard is given as an infusion into a vein. A healthcare provider will give you this injection.

Totect is usually started within 6 hours after extravasation, and continued once daily for 3 days.

Zinecard is usually started 15 minutes before you receive your doxorubicin infusion. Zinecard is not given with your first dose of doxorubicin, but only after you've received prior doxorubicin doses up to a certain total amount.

Zinecard can add to bone marrow suppression caused by chemotherapy. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.

What happens if I miss a dose?

Because Zinecard is provided by a medical care specialist as part of your chemotherapy therapy, you are not likely to miss a dosage.

Call your physician for guidelines if you miss your radiation treatment visit.

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What happens if I overdose?

Seek emergency situation medical interest or call the Toxin Help line at 1-800-222-1222.

Prevent being near individuals who are sick or have infections. Inform your medical professional at the same time if you establish indicators of infection.

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What other drugs will affect Zinecard?

Tell your physician about all your other medicines, especially:

  • various other cancer medicines; or
  • dimethyl sulfoxide (DMSO).

This list is not total. Other medicines might influence Zinecard, consisting of prescription and over the counter medications, vitamins, and herbal items. Not all feasible medication interactions are provided right here.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.