Zmax (Oral)

Azithromycin is used to treat certain bacterial infections in many different parts of the body. This medicine may mask or delay the signs and symptoms of syphilis. It is not effective against syphilis infections.

Azithromycin belongs to the class of drugs called macrolide prescription antibiotics. It works by killing germs or stopping their development. Nevertheless, this medication will certainly not work for colds, flu, or other infection infections.

This medicine is offered only with your physician's prescription.

It is very important that your physician check the development of you or your child at routine check outs to make certain this medication is functioning correctly. Blood and pee examinations might be required to check for unwanted impacts.

If you or your youngster's signs and symptoms do not improve within a couple of days, or if they worsen, consult your doctor.

This medicine might create major allergic reactions, including anaphylaxis and angioedema, which can be deadly and call for prompt clinical attention. Call your medical professional right now if you or your child have a rash, itching, hives, hoarseness, trouble breathing, problem ingesting, or any type of swelling of your hands, face, or mouth after you take this medicine.

Significant skin responses, including Stevens-Johnson syndrome, severe generalized exanthematous pustulosis, hazardous skin necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS) can accompany this medication. Get in touch with your medical professional as soon as possible if you or your child have black, tarry feceses, blistering, peeling, or helping to loosen of the skin, upper body pain, chills, cough, diarrhea, itching, joint or muscle pain, painful or tough urination, red inflamed eyes, red skin lesions, typically with a purple facility, aching throat, sores, ulcers, or white places in the mouth or on the lips, swollen glands, unusual blood loss or bruising or unusual exhaustion or weak point while you are using this medication.

Get in touch with your medical professional as soon as possible if you or your kid have discomfort or tenderness in the upper tummy, light feceses, dark pee, anorexia nervosa, nausea, uncommon fatigue or weak point, or yellow eyes or skin. These could be signs and symptoms of a significant liver trouble.

Call your child's doctor right now if your kid feels irritable or vomits after feeding. These might be signs of a problem called infantile hypertrophic pyloric constriction.

Azithromycin might cause diarrhea, and sometimes it can be severe. It may take place 2 months or more after you quit utilizing this medicine. Do not take any medicine to treat diarrhea without first monitoring with your doctor. Diarrhea medications may make the looseness of the bowels worse or make it last longer. If you or your child have any type of inquiries about this or if light looseness of the bowels proceeds or gets worse, talk to your physician.

This medication can cause changes in heart rhythms, consisting of QT prolongation. It may transform the method your heart beats and cause fainting or severe adverse effects in some people. Contact your doctor today if you or your child have any signs and symptoms of heart rhythm issues, consisting of quick, pounding, or irregular heart beats.

This medication may boost the risk of significant heart or capillary problems. Call your physician right now if you have actually obscured vision, upper body discomfort, complication, faintness, lightheadedness, fainting, fast or uneven heart beat, trouble breathing, or uncommon tiredness or weak point.

Do not take other medicines unless they have actually been talked about with your physician. This consists of prescription or nonprescription (non-prescription [OTC] medications and organic or vitamin supplements.

In making a decision to utilize a medication, the risks of taking the medicine should be weighed versus the great it will do. This is a choice you and your physician will make. For this medicine, the adhering to must be taken into consideration:

Allergies

Tell your doctor if you have actually ever had any type of unusual or allergy to this medication or any various other medications. Additionally tell your healthcare specialist if you have any various other types of allergic reactions, such as to foods, dyes, preservatives, or animals. For non-prescription items, reviewed the tag or package ingredients meticulously.

Pediatric

Suitable studies have not been executed on the connection old to the effects of azithromycin to deal with sinusitis in kids or to treat pneumonia in youngsters more youthful than 6 months of age. Security and efficiency have not been established.

Appropriate studies have not been carried out on the relationship of age to the results of azithromycin oral suspension and tablets to treat pharyngitis or tonsillitis in youngsters more youthful than 2 years of age. Safety and effectiveness have not been developed.

Geriatric

Proper researches done to date have not demonstrated geriatric-specific problems that would restrict the efficiency of azithromycin in the elderly. Nonetheless, senior people are most likely to have heart rhythm troubles (eg, torsades de pointes) which might require caution in patients obtaining azithromycin.

Breast Feeding

There are no appropriate studies in females for figuring out baby danger when utilizing this medication throughout breastfeeding. Weigh the prospective advantages versus the prospective dangers before taking this medicine while breastfeeding.

Interactions with Medicines

Although specific medications need to not be used together in all, in other cases 2 different medicines may be utilized with each other even if a communication might occur. In these instances, your physician might want to alter the dose, or other precautions may be needed. When you are taking this medication, it is specifically essential that your health care professional know if you are taking any one of the medications listed below. The following interactions have actually been picked on the basis of their possible importance and are not necessarily all-inclusive.

Using this medication with any one of the complying with medications is not suggested. Your doctor might determine not to treat you with this drug or alter several of the various other medicines you take.

• Bepridil
• Cisapride
• Dronedarone
• Levoketoconazole
• Pimozide
• Piperaquine
• Saquinavir
• Sparfloxacin
• Terfenadine
• Thioridazine
• Ziprasidone

Utilizing this medication with any of the complying with medicines is typically not advised, yet might be called for sometimes. If both medications are suggested together, your medical professional might alter the dose or just how frequently you utilize one or both of the medicines.

• Acecainide
• Adagrasib
• Alfuzosin
• Amiodarone
• Amisulpride
• Amitriptyline
• Amoxapine
• Anagrelide
• Apomorphine
• Aripiprazole
• Aripiprazole Lauroxil
• Arsenic Trioxide
• Asenapine
• Astemizole
• Atazanavir
• Azimilide
• Bretylium
• Buprenorphine
• Buserelin
• Ceritinib
• Chloroquine
• Chlorpromazine
• Cholera Vaccine, Live
• Ciprofloxacin
• Citalopram
• Clarithromycin
• Clofazimine
• Clomipramine
• Clothiapine
• Clozapine
• Crizotinib
• Dabrafenib
• Dasatinib
• Degarelix
• Delamanid
• Desipramine
• Deslorelin
• Deutetrabenazine
• Dexmedetomidine
• Digoxin
• Dihydroergotamine
• Disopyramide
• Dofetilide
• Dolasetron
• Domperidone
• Donepezil
• Doxorubicin
• Doxorubicin Hydrochloride Liposome
• Droperidol
• Edoxaban
• Efavirenz
• Encorafenib
• Entrectinib
• Ergotamine
• Erythromycin
• Escitalopram
• Etrasimod
• Fexinidazole
• Fingolimod
• Flecainide
• Fluconazole
• Fluoxetine
• Formoterol
• Foscarnet
• Fostemsavir
• Gatifloxacin
• Gemifloxacin
• Gepirone
• Glasdegib
• Gonadorelin
• Goserelin
• Granisetron
• Halofantrine
• Haloperidol
• Histrelin
• Hydroxychloroquine
• Hydroxyzine
• Ibutilide
• Iloperidone
• Imipramine
• Inotuzumab Ozogamicin
• Ivabradine
• Ivosidenib
• Ketoconazole
• Lapatinib
• Lefamulin
• Lenvatinib
• Leuprolide
• Levofloxacin
• Lofexidine
• Lopinavir
• Lumefantrine
• Macimorelin
• Mefloquine
• Methadone
• Methotrexate
• Metronidazole
• Mifepristone
• Mirtazapine
• Mobocertinib
• Morphine
• Morphine Sulfate Liposome
• Moxifloxacin
• Nafarelin
• Nilotinib
• Norfloxacin
• Nortriptyline
• Octreotide
• Ofloxacin
• Olanzapine
• Ondansetron
• Osilodrostat
• Osimertinib
• Oxaliplatin
• Ozanimod
• Pacritinib
• Paliperidone
• Panobinostat
• Paroxetine
• Pasireotide
• Pazopanib
• Pentamidine
• Phenobarbital
• Pimavanserin
• Pitolisant
• Pixantrone
• Ponesimod
• Posaconazole
• Primidone
• Procainamide
• Prochlorperazine
• Promethazine
• Propafenone
• Protriptyline
• Quetiapine
• Quinidine
• Quinine
• Quizartinib
• Ranolazine
• Relugolix
• Ribociclib
• Risperidone
• Selpercatinib
• Sematilide
• Sertraline
• Sevoflurane
• Simvastatin
• Siponimod
• Sodium Phosphate
• Sodium Phosphate, Dibasic
• Sodium Phosphate, Monobasic
• Solifenacin
• Sorafenib
• Sotalol
• Sulpiride
• Sunitinib
• Tacrolimus
• Tedisamil
• Telithromycin
• Tetrabenazine
• Toremifene
• Trazodone
• Triclabendazole
• Trifluoperazine
• Trimipramine
• Triptorelin
• Vandetanib
• Vardenafil
• Vemurafenib
• Vilanterol
• Vinflunine
• Voclosporin
• Voriconazole
• Warfarin
• Zuclopenthixol

Using this medication with any one of the complying with medicines might trigger an enhanced danger of specific adverse effects, but utilizing both medications may be the most effective therapy for you. If both medications are prescribed with each other, your doctor may transform the dose or just how typically you use one or both of the medications.

• Atorvastatin
• Lovastatin
• Nelfinavir
• Rifabutin
• Theophylline

Interactions with Food/Tobacco/Alcohol

Certain medicines need to not be made use of at or around the time of eating food or eating particular sorts of food given that interactions might happen. Making use of alcohol or tobacco with certain medicines might additionally trigger interactions to occur. Talk about with your medical care specialist the use of your medication with food, alcohol, or tobacco.

Other Medical Problems

The visibility of various other medical issues may impact using this medicine. Make sure you inform your medical professional if you have any type of other medical troubles, particularly:

• Allergy to any macrolide and ketolide antibiotic (eg, clarithromycin, erythromycin, telithromycin, Biaxin ®, Ery-tab ®, or

Ketek ®) or- Liver condition with prior azithromycin usage, history of-- Should not be made use of in patients with this condition.

• Bacteremia (blood infection) or
• Cystic fibrosis or
• Infections, nosocomial or hospital-acquired or
• Weak body immune system or
• Weakened physical condition-- Should not be used in clients with these problems to deal with pneumonia.

• Bradycardia (slow heartbeat) or
• Congestive heart failure or
• Diarrhea or
• Heart disease or
• Heart rhythm troubles (eg, QT prolongation, torsades de pointes, bradyarrhythmias), background of or
• Hypokalemia (reduced potassium in the blood), uncorrected or
• Hypomagnesemia (low magnesium in the blood), uncorrected or
• Myasthenia gravis (extreme muscle weak point)-- Use with caution. May make these problems worse.

• Kidney illness, severe or
• Liver disease-- Use with caution. The effects might be increased as a result of slower elimination of the medicine from the body.

In addition to its necessary effects, a medication may cause some unwanted impacts. Although not every one of these side effects may take place, if they do occur they might need medical attention.

Check with your physician immediately if any of the complying with side effects take place:

More common

• Diarrhea
• loosened feceses

Much less usual

• Blistering, crusting, inflammation, itching, or reddening of the skin
• broken, completely dry, or scaly skin
• high temperature
• swelling

Rare

• Blistering, peeling off, or helping to loosen of the skin
• bloody or cloudy pee
• bloody, black, or tarry feceses
• body aches or pain
• burning while urinating
• breast pain or rigidity
• cools
• blockage
• cough increased
• coughing generating mucous
• dark urine
• difficult or struggled breathing
• hard or painful peeing
• dizziness
• drowsiness
• dryness or soreness of the throat
• earache
• fainting
• quickly, irregular, pounding, or competing heart beat or pulse
• basic sensation of pain or health problem
• frustration
• indigestion
• irregular or sluggish heart price
• itching or rash
• joint or muscle mass pain
• big, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• light feceses
• anorexia nervosa
• muscle pains and pains
• nausea or vomiting
• loud breathing
• death of gas
• red skin lesions, frequently with a purple center
• red, aggravated eyes
• soreness or swelling in the ear
• drippy nose
• shuddering
• sneezing
• sores, ulcers, or white spots on the lips or in the mouth
• belly discomfort, proceeding
• stomach discomfort, fullness, or discomfort
• stale nose
• sweating
• swelling of the face, ankle joints, hands, feet, or lower legs
• tender, swollen glands in the neck
• trouble with sleeping
• problem with swallowing
• undesirable breath odor
• uncommon blood loss or wounding
• unusual fatigue or weak point
• upper appropriate stomach or belly discomfort
• voice changes
• throwing up of blood
• yellow eyes or skin

Incidence not recognized

• Bleeding periodontals
• bloating
• blood in the urine or feceses
• blurred vision
• change in hearing
• clay-colored feceses
• coma
• confusion
• bowel irregularity
• continuing buzzing or buzzing or other unusual noise in the ears
• reduced urine result
• anxiety
• diarrhea, watery and serious, which may additionally be bloody
• lightheadedness, fatigue, or lightheadedness when standing up unexpectedly from a lying or sitting placement
• fainting
• greatly reduced regularity of peeing or quantity of pee
• hives
• hostility
• enhanced thirst
• irritation
• lethargy
• loss of hearing
• lower back or side discomfort
• muscle mass twitching
• no high blood pressure or pulse
• pains in the belly, side, or abdomen, potentially emitting to the back
• pale skin
• determine red places on the skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• quick weight gain
• seizures
• tummy aches or inflammation
• stopping of heart
• amazement
• unfamiliarity
• uncommon weight management

Some side effects might take place that generally do not need medical focus. These adverse effects might vanish during therapy as your body gets used to the medicine. Likewise, your healthcare expert might be able to inform you about ways to stop or decrease several of these adverse effects. Get in touch with your health care professional if any of the following negative effects continue or are aggravating or if you have any type of concerns concerning them:

Rare

• Acid or sour tummy
• aggressive or upset
• bad, uncommon, or undesirable (after) taste
• belching
• shedding feeling in the breast or belly
• burning, creeping, itching, tingling, tingling, "pins and needles", or tingling sensations
• adjustment in taste
• changes in the shade of the tongue
• weeping
• depersonalization
• dry mouth
• dysphoria
• ecstasy
• excess air or gas in the stomach or intestines
• feeling of continuous motion of self or surroundings
• full feeling
• heartburn
• hyperventilation
• boost in body language
• itchiness of the vaginal area or genital area
• lack or loss of toughness
• mental anxiety
• anxiety
• pain throughout sexual intercourse
• paranoia
• quick to respond or overreact psychologically
• rapidly altering state of minds
• breakout with flat sores or little raised sores on the skin
• inflammation of the skin
• restlessness
• experience of rotating
• trembling
• drowsiness or unusual drowsiness
• indigestion
• thick, white genital discharge without any smell or with a moderate smell
• white spots in the mouth, tongue, or throat

Incidence not known

• Difficulty with relocating
• increased sensitivity of the skin to sunlight
• muscle mass discomfort or rigidity
• discomfort in the joints
• redness or various other staining of the skin
• extreme sunburn
• difficulty resting still

Opposite side results not noted may likewise happen in some people. If you notice any various other results, get in touch with your health care expert.

Call your medical professional for clinical advice regarding adverse effects. You might report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Zithromax
• Zithromax Tri-Pak
• Zithromax Z-Pak
• Zmax

Readily Available Dosage Forms:

• Powder for Suspension, Extended Release
• Tablet
• Powder for Suspension

Healing Class: Antibiotic

Chemical Class: Macrolide

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You may take Zithromax® oral liquid or tablets with or without food.

Shake well the bottle of Zithromax® oral liquid before each use. Measure your dose correctly with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Measure the Zmax® extended-release oral suspension with a marked measuring spoon, syringe, or cup. You or your child must take this medicine within 12 hours after it has been mixed with water. It is best to take the Zmax® extended-release oral suspension on an empty stomach or at least 1 hour before or 2 hours after a meal. If your child does not use all of the medicine in the bottle, throw it away after you give the dose.

If you or your child vomits within one hour of taking the Zmax® extended-release oral suspension, call your doctor right away to see if more medicine is needed.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

If you are taking aluminum or magnesium-containing antacids, do not take them at the same time that you take Zithromax®. These medicines may keep azithromycin from working properly. However, you can take antacids with Zmax®.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (extended-release suspension): For treatment of pneumonia: Adults—2 grams (g) once as a single dose. Children weighing 34 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 grams once a day, taken as a single dose. Children 6 months of age and older weighing less than 34 kg—Dose is based on body weight and must be determined by your doctor. The dose is usually 60 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. For treatment of sinusitis: Adults—2 grams (g) once a day as a single dose. Children—Use and dose must be determined by your doctor.
• For oral dosage forms (suspension or tablets): For treatment of infections: Adults—500 to 2000 milligrams (mg) once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 250 to 500 mg once a day for several days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 30 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 5 to 10 mg per kg of body weight once a day for several days. Children younger than 6 months of age—Use and dose must be determined by your doctor. For treatment of pharyngitis or tonsillitis: Adults—500 milligrams (mg) on Day 1 (the first day), taken as a single dose. Then, 250 mg on Day 2 through Day 5. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight once a day for 5 days. Children younger than 2 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Zithromax® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

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