On this page · 9 sections

Zofran ODT

Generic name: ondansetron (oral)

Last updated November 5, 2026 0 views
Share

What is Zofran ODT?

Zofran ODT is utilized to stop queasiness and throwing up that might happen with certain cancer medicines (chemotherapy), or after surgical treatment, or radiation therapy.

Zofran ODT might be utilized for objectives not detailed in this medicine guide.

This section was rewritten for readability and reviewed for meaning.

How should I take Zofran ODT?

Follow all instructions on your prescription label and check out all drug guides or direction sheets. Make use of the medicine precisely as routed.

Zofran ODT is usually taken prior to surgery, radiation treatment, or radiation therapy. Follow your medical professional's dosing directions very meticulously.

Step liquid medication with the supplied measuring device (not a kitchen area spoon).

To take the by mouth degenerating tablet computer:

  • Keep the tablet computer in its sore pack until you are ready to take it. Open the package and peel off back the aluminum foil. Usage completely dry hands to remove the orally disintegrating tablet computer and location it in your mouth. Do not press a tablet computer with the foil or you might harm the tablet computer.
  • Allow the orally breaking down tablet computer to liquify in your mouth without eating. Do not ingest entire.

Shop in the initial container at space temperature away from dampness, warm, and light. Store liquid medicine in an upright position.

This section was rewritten for readability and reviewed for meaning.

Warnings

Tell your doctor regarding all your other medicines. Some medicines ought to not be used with Zofran ODT.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You need to not use Zofran ODT if you dislike it or similar medications (dolasetron, granisetron, palonosetron).

Some drugs need to not be used with Zofran ODT. Your treatment strategy may alter if you likewise use apomorphine.

Tell your medical professional if you have or have actually ever before had:

  • an electrolyte imbalance (such as reduced blood levels of potassium or magnesium);.
  • congestive heart failure, slow heartbeats;.
  • heart rhythm condition such as lengthy QT disorder (in you or a family member);.
  • an obstruction in the stomach or intestinal tracts, a modification in bowel behaviors;.
  • a surgical treatment on your tummy or intestines; or.
  • severe liver illness.

The orally disintegrating tablet computer might consist of phenylalanine and could be dangerous if you have phenylketonuria (PKU).

Tell your medical professional if you additionally use stimulant medication, opioid medicine, natural products, or medicine for depression, mental illness, Parkinson's condition, migraine headaches, significant infections, or prevention of queasiness and throwing up. An interaction with Zofran ODT could create a significant condition called serotonin disorder.

Tell your physician if you are pregnant or breastfeeding.

Zofran ODT is not accepted for use by anybody younger than 4 years old.

This section was rewritten for readability and reviewed for meaning.

Zofran ODT side effects

Get emergency situation clinical aid if you have indications of an allergy: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Seek clinical focus as soon as possible if you have signs and symptoms of serotonin syndrome such as: anxiety, hallucinations, fever, sweating, shivering, rapid heart price, muscle mass rigidity, shivering, loss of control, queasiness, vomiting, or diarrhea.

Seek emergency clinical assistance if you have signs of a heart attack: breast discomfort that infects your jaw or shoulder, nausea, and sweating.

Zofran ODT may cause significant adverse effects. Call your physician at the same time if you have:

  • severe tummy pain, bloating, irregularity, or any kind of adjustment in bowel routines; or
  • wooziness, feeling lightheaded, passing out, slow, fast, or irregular heart beats.

Common side effects of Zofran ODT might consist of:

  • diarrhea or bowel irregularity;
  • migraine;
  • lack of breath, rapid breathing, fast heartbeats; or
  • feeling unwell, tiredness.

This is not a complete listing of adverse effects and others may take place. Call your doctor for clinical recommendations concerning side effects. You might report negative effects to FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

What happens if I miss a dose?

Zofran ODT is utilized when needed. If you are on a dosing timetable, avoid any type of missed dose. Do not make use of 2 dosages at once.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Look for emergency clinical attention or call the Poisonous substance Help line at 1-800-222-1222.

Follow your medical professional's guidelines about any restrictions on food, beverages, or activity.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect Zofran ODT?

Zofran ODT can create a serious heart trouble. Your risk might be greater if you also use specific other medicines for infections, asthma, heart issues, hypertension, anxiety, mental illness, cancer cells, jungle fever, or HIV.

Many drugs can affect Zofran ODT. This includes prescription and over the counter medicines, vitamins, and organic items. Not all possible interactions are listed right here. Tell your medical professional about all various other medications you use.

This section was rewritten for readability and reviewed for meaning.

Common questions about Zofran ODT

Can you take ondansetron while pregnant?
Although ondansetron is not specifically approved by the FDA to treat nausea and vomiting during pregnancy (NVP), its use is common, and approximately 25% of pregnant women are prescribed ondansetron to treat NVP. Overall, studies show the use of ondansetron appears to be associated with an additional 3 instances of oral cleft defects (such as cleft lip or cleft palate) for every 10,000 women exposed to ondansetron during their first trimester. There may also be a very slight increased risk of a type of heart defect called a ventricular septal defect, but no apparent increased risk of other birth defects, miscarriage, or fetal death. Continue reading
How long before a meal should you take ondansetron?
If you are taking ondansetron for nausea that occurs with meals, then the standard tablet should be taken half an hour to 1 hour before meals, and the orally disintegrating tablet or oral soluble film can be taken 15 minutes before meals. However, if you are taking ondansetron for constant, all day nausea then it should be taken at regular intervals during the day as prescribed, with or without food.
How often can you take ondansetron?
You can take ondansetron more frequently initially, for example, if you are taking it to prevent or treat nausea of vomiting from chemotherapy you can take 4mg then follow up with another 4mg dose at 4 and 8 hours after the first dose. The following day you should only take it every 8 hours (3 times a day). If you continue taking ondansetron more frequently than this you are at higher risk of side effects such as constipation, headache, or heart effects.
Chemo side effects: What should I expect and how to cope?
Chemotherapy is a drug treatment used to kill fast-growing cancer cells in your body. While chemotherapy is an effective treatment for many types of cancer, it can also damage healthy cells that divide quickly, such as those in your hair follicles, digestive tract, and bone marrow. This widespread effect on healthy tissue is what causes the various side effects associated with chemotherapy treatment. Continue reading
How long does ondansetron take to work?
Oral ondansetron usually starts to work within 30 minutes, though it may take up to two hours to reach full effect. Typical timing is: 30 minutes before chemotherapy, 1 hour before surgery, 1 to 2 hours before radiation therapy. Continue reading
Does ondansetron make you sleepy?
Yes, ondansetron (Zofran) might make you feel sleepy or tired. Ondansetron injection for the treatment of post-operative nausea and vomiting has been reported to cause drowsiness or sedation in 8% of patients vs. 7% of those using a placebo (an inactive treatment). Malaise (generally feeling unwell) and fatigue (tiredness or lack of energy) have also been reported in 13% of patients (vs. 2% placebo) when it is used orally for the prevention of chemotherapy-induced nausea and vomiting. Continue reading

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
General medicine information Consumer-friendly language

Content is provided for education and is not medical advice. See our medical disclaimer.