Zydone (Oral)

Hydrocodone and acetaminophen combination is utilized to relieve discomfort extreme adequate to require opioid treatment and when other discomfort medications did not function well adequate or can not be endured.

Acetaminophen is utilized to eliminate pain and minimize fever in patients. It does not come to be addictive when taken for a long time. Yet acetaminophen may create other unwanted impacts when absorbed large dosages, consisting of liver damages.

Hydrocodone belongs to the group of medicines called numbing analgesics (discomfort medicines). It acts upon the main nerve system (CNS) to soothe discomfort, and stops or stops coughing.

When hydrocodone is utilized for a long time, it may come to be addictive, triggering psychological or physical dependence. Nevertheless, individuals who have continuing pain ought to not allow the fear of reliance keep them from making use of narcotics to relieve their pain. Psychological reliance (addiction) is not most likely to take place when narcotics are made use of for this function. Physical dependancy might result in withdrawal adverse effects if therapy is stopped all of a sudden. Nevertheless, serious withdrawal negative effects can generally be protected against by gradually reducing the dose over a time period before treatment is stopped completely.

This medication is offered just under a restricted circulation program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.

It is really crucial that your medical professional examine your or your kid's progress while utilizing this medication, specifically within the first 24 to 72 hours of therapy. This will permit your doctor to see if the medicine is working effectively and to determine if you or your kid must continue to take it. Blood and urine examinations may be needed to check for undesirable impacts.

Do not utilize this medicine if you are utilizing or have utilized an MAO prevention (eg, isocarboxazid [Marplan ®], linezolid [Zyvox ®], phenelzine [Nardil ®], selegiline [Eldepryl ®], tranylcypromine [Parnate ®] within the past 14 days.

It is against the legislation and harmful for anyone else to use your medicine. Keep your extra tablet computers in a risk-free and protected area. People who are addicted to drugs might want to swipe this medicine.

This medication will certainly contribute to the impacts of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergic reactions or colds, sedatives, depressants, or sleeping medicine, other prescription discomfort medicine or narcotics, medication for seizures or barbiturates, muscle mass relaxants, or anesthetics (numbing medications), including some oral anesthetics. Also, there may be a greater risk of liver damages if you consume alcohol 3 or more alcohols while you are taking acetaminophen. Do not consume liquors, and talk to your doctor before taking any of these medications while you are using this medication.

This medication may be addictive. If you really feel that the medication is not working also, do not make use of more than your suggested dosage.

If you assume you or somebody else might have taken an overdose of this medicine, get emergency aid simultaneously. Your medical professional may likewise offer naloxone to treat an overdose. Indications of an overdose include: cold, clammy skin, coughing that often produces a pink frothy sputum, dark pee, hard or trouble breathing, irregular, quick or sluggish, or shallow breathing, nausea, vomiting, discomfort in the top tummy, pale or blue lips, fingernails, or skin, pinpoint students of the eyes, or yellow eyes or skin.

This medicine may cause sleep-related breathing problems (eg, sleep apnea, sleep-related hypoxemia). Your medical professional might decrease your dosage if you have sleep apnea (quit breathing for brief periods during rest) while using this medication.

This medication might create adrenal gland issues. Consult your physician today if you have dimming of the skin, looseness of the bowels, wooziness, fainting, anorexia nervosa, mental clinical depression, nausea, skin rash, unusual exhaustion or weakness, or throwing up.

Check with your physician today if you have discomfort or inflammation in the top stomach, pale stools, dark pee, loss of appetite, queasiness, unusual exhaustion or weakness, or yellow eyes or skin. These can be signs of a significant liver problem.

This medication may trigger severe skin responses (eg, severe generalised exanthematous pustulosis, Stevens-Johnson disorder, hazardous skin necrolysis). Get in touch with your medical professional immediately if you have blistering, peeling, or loosening of the skin, chills, coughing, looseness of the bowels, itching, joint or muscle mass discomfort, red irritated eyes, red skin sores, commonly with a purple facility, aching throat, sores, abscess, or white areas in the mouth or on the lips, or uncommon tiredness or weakness.

This medicine may cause a severe type of allergy called anaphylaxis, which can be serious and requires immediate medical interest. Call your doctor right away if you have a breakout, itching, hoarseness, difficulty breathing, difficulty ingesting, or any kind of swelling of your hands, face, or mouth while you are using this medicine.

Dizziness, impaired thinking, or fainting may occur when you stand up unexpectedly from an existing or resting position. Getting up slowly might aid decrease this problem. Likewise, relaxing for a while may relieve wooziness or impaired thinking.

This medication may make you woozy, sluggish, or lightheaded. Do not drive or do anything else that might be hazardous up until you recognize exactly how this medicine affects you.

Using narcotics for a very long time can cause serious irregular bowel movements. To prevent this, your physician may route you or your youngster to take laxatives, consume a great deal of liquids, or boost the quantity of fiber in your diet regimen. Make sure to follow the instructions carefully, due to the fact that proceeding irregular bowel movements can cause much more serious issues.

Prior to you or your child have any type of clinical examinations, inform the medical physician accountable that you are taking this medicine. The results of specific examinations might be affected by this medication.

Do not transform your dosage or unexpectedly quit utilizing this medication without first checking with your medical professional. Your medical professional may desire you or your child to slowly lower the amount you are making use of prior to quiting it entirely. This might aid prevent intensifying of your condition and minimize the opportunity of withdrawal signs and symptoms, consisting of tummy cramps, anxiety, fever, queasiness, dripping nose, sweating, shakes, or problem with sleeping.

Utilizing this medication while you are expecting may trigger significant unwanted effects, consisting of neonatal withdrawal syndrome in your newborn baby. Tell your doctor as soon as possible if your kid has an unusual sleep pattern, diarrhea, a shrill cry, impatience, shakiness or tremors, sneezing, weight-loss, vomiting, yawning, or failing to put on weight. Consult your medical professional right away if you assume you are expectant or if you plan to conceive while utilizing this medication.

Check with your doctor right now if you have anxiousness, restlessness, a fast heart beat, high temperature, sweating, muscular tissue convulsions, shivering, queasiness, throwing up, diarrhea, or see or hear points that are not there. These might be signs and symptoms of a significant problem called serotonin disorder. Your risk might be greater if you also take particular other medications that influence serotonin levels in your body.

Using way too much of this medication might create the inability to conceive (not able to have children). Talk with your physician before using this medicine if you prepare to have kids.

Do not take various other medications unless they have actually been gone over with your doctor. This consists of prescription or nonprescription (non-prescription [OTC] medications and organic or vitamin supplements.

In making a decision to utilize a medicine, the threats of taking the medication must be weighed against the excellent it will certainly do. This is a decision you and your doctor will make. For this medicine, the complying with must be considered:

Allergies

Inform your physician if you have actually ever had any type of uncommon or allergic reaction to this medicine or any various other medicines. Likewise inform your health care professional if you have any type of various other sorts of allergic reactions, such as to foods, dyes, chemicals, or animals. For non-prescription products, checked out the label or package active ingredients very carefully.

Pediatric

Appropriate studies have actually not been carried out on the partnership of age to the effects of hydrocodone and acetaminophen mix pills and tablets in the pediatric population. Safety and security and efficiency have not been established.

Ideal studies performed to day have not shown pediatric-specific issues that would restrict the efficiency of hydrocodone and acetaminophen combination oral option in youngsters 2 years of age and older. However, safety and efficacy have not been established in children more youthful than 2 years old.

Geriatric

Appropriate studies carried out to day have actually not demonstrated geriatric-specific problems that would certainly restrict the effectiveness of hydrocodone and acetaminophen mix in the senior. Nonetheless, elderly individuals are more probable to have confusion and sleepiness, and age-related lung, liver, kidney, or heart troubles, which may require caution and an adjustment in the dose for people obtaining hydrocodone and acetaminophen combination.

Breast Feeding

There are no ample research studies in females for determining infant danger when using this medicine during breastfeeding. Evaluate the possible advantages versus the potential risks prior to taking this medication while breastfeeding.

Interactions with Medicines

Although particular medicines must not be made use of together in any way, in various other instances two various medicines may be made use of together also if an interaction could happen. In these instances, your doctor may wish to alter the dosage, or other precautions might be required. When you are taking this medicine, it is specifically vital that your healthcare expert recognize if you are taking any of the medicines listed here. The adhering to communications have been selected on the basis of their potential importance and are not necessarily all-inclusive.

Utilizing this medication with any of the complying with medications is not recommended. Your medical professional might decide not to treat you with this medication or change some of the other medicines you take.

• Nalmefene
• Naltrexone
• Safinamide
• Samidorphan

Utilizing this medicine with any of the following medicines is typically not suggested, yet may be needed in some cases. If both medications are prescribed with each other, your physician may transform the dosage or exactly how typically you utilize one or both of the medications.

• Abametapir
• Acepromazine
• Alfentanil
• Almotriptan
• Alprazolam
• Amifampridine
• Amineptine
• Amiodarone
• Amitriptyline
• Amitriptylinoxide
• Amobarbital
• Amoxapine
• Amphetamine
• Amprenavir
• Anileridine
• Aprepitant
• Aripiprazole
• Armodafinil
• Asenapine
• Atazanavir
• Baclofen
• Benperidol
• Benzphetamine
• Boceprevir
• Bosentan
• Bromazepam
• Bromopride
• Brompheniramine
• Buprenorphine
• Bupropion
• Buspirone
• Butabarbital
• Butorphanol
• Calcium Oxybate
• Cannabidiol
• Cannabis
• Carbamazepine
• Carbinoxamine
• Carisoprodol
• Carphenazine
• Ceritinib
• Cetirizine
• Chloral Hydrate
• Chlordiazepoxide
• Chlorpheniramine
• Chlorpromazine
• Chlorzoxazone
• Ciprofloxacin
• Citalopram
• Clarithromycin
• Clobazam
• Clomipramine
• Clonazepam
• Clopidogrel
• Clorazepate
• Clozapine
• Cobicistat
• Cocaine
• Codeine
• Conivaptan
• Crizotinib
• Cyclobenzaprine
• Cyclosporine
• Daridorexant
• Darunavir
• Dasabuvir
• Delavirdine
• Desipramine
• Desmopressin
• Desvenlafaxine
• Dexamethasone
• Dexmedetomidine
• Dextroamphetamine
• Dextromethorphan
• Dezocine
• Diazepam
• Dibenzepin
• Dichloralphenazone
• Difenoxin
• Dihydrocodeine
• Diltiazem
• Diphenhydramine
• Diphenoxylate
• Dolasetron
• Donepezil
• Doxepin
• Doxylamine
• Dronedarone
• Droperidol
• Duloxetine
• Efavirenz
• Eletriptan
• Enflurane
• Enzalutamide
• Erythromycin
• Escitalopram
• Esketamine
• Eslicarbazepine Acetate
• Estazolam
• Eszopiclone
• Ethchlorvynol
• Ethopropazine
• Ethylmorphine
• Etravirine
• Fedratinib
• Fenfluramine
• Fentanyl
• Fexinidazole
• Flibanserin
• Fluconazole
• Fluoxetine
• Fluphenazine
• Flurazepam
• Fluspirilene
• Fluvoxamine
• Fosamprenavir
• Fosaprepitant
• Fosnetupitant
• Fosphenytoin
• Fospropofol
• Frovatriptan
• Furazolidone
• Gabapentin
• Gabapentin Enacarbil
• Gepirone
• Granisetron
• Halazepam
• Haloperidol
• Halothane
• Hexobarbital
• Hydromorphone
• Hydroxytryptophan
• Hydroxyzine
• Idelalisib
• Imatinib
• Imipramine
• Indinavir
• Iproniazid
• Isocarboxazid
• Isoflurane
• Isoniazid
• Itraconazole
• Ivacaftor
• Ketamine
• Ketazolam
• Ketobemidone
• Ketoconazole
• Lacosamide
• Lasmiditan
• Lemborexant
• Lenacapavir
• Levocetirizine
• Levomilnacipran
• Levorphanol
• Linezolid
• Lisdexamfetamine
• Lithium
• Lofepramine
• Lofexidine
• Lomitapide
• Lopinavir
• Lorazepam
• Lorcaserin
• Loxapine
• Lumacaftor
• Magnesium Oxybate
• Mavacamten
• Meclizine
• Melitracen
• Melperone
• Meperidine
• Mephobarbital
• Meprobamate
• Meptazinol
• Mesoridazine
• Metaxalone
• Methadone
• Methamphetamine
• Methdilazine
• Methocarbamol
• Methohexital
• Methotrimeprazine
• Methylene Blue
• Metoclopramide
• Mibefradil
• Midazolam
• Mifepristone
• Milnacipran
• Mirtazapine
• Mitotane
• Moclobemide
• Modafinil
• Molindone
• Moricizine
• Morphine
• Morphine Sulfate Liposome
• Nafcillin
• Nalbuphine
• Naratriptan
• Nefazodone
• Nelfinavir
• Netupitant
• Nevirapine
• Nialamide
• Nicomorphine
• Nilotinib
• Nitrazepam
• Nitrous Oxide
• Nortriptyline
• Olanzapine
• Omaveloxolone
• Ombitasvir
• Ondansetron
• Opipramol
• Opium
• Opium Alkaloids
• Orphenadrine
• Oxazepam
• Oxcarbazepine
• Oxycodone
• Oxymorphone
• Ozanimod
• Palbociclib
• Palonosetron
• Papaveretum
• Paregoric
• Paritaprevir
• Paroxetine
• Pentazocine
• Pentobarbital
• Perampanel
• Perazine
• Periciazine
• Perphenazine
• Phenelzine
• Phenobarbital
• Phenytoin
• Piperacetazine
• Pipotiazine
• Piritramide
• Pixantrone
• Pneumococcal 13-Valent Vaccine, Diphtheria Conjugate
• Posaconazole
• Potassium Oxybate
• Prazepam
• Prednisone
• Pregabalin
• Primidone
• Procarbazine
• Prochlorperazine
• Promazine
• Promethazine
• Propofol
• Protriptyline
• Quazepam
• Quetiapine
• Ramelteon
• Ranitidine
• Ranolazine
• Rasagiline
• Remifentanil
• Remimazolam
• Remoxipride
• Rifabutin
• Rifampin
• Rifapentine
• Ritonavir
• Rizatriptan
• Ropeginterferon Alfa-2b-njft
• Saquinavir
• Scopolamine
• Secobarbital
• Selegiline
• Sertindole
• Sertraline
• Sibutramine
• Sodium Oxybate
• St John's Wort
• Sufentanil
• Sulpiride
• Sumatriptan
• Suvorexant
• Tapentadol
• Telaprevir
• Telithromycin
• Temazepam
• Thiethylperazine
• Thiopental
• Thiopropazate
• Thioridazine
• Tianeptine
• Tilidine
• Tizanidine
• Tolonium Chloride
• Topiramate
• Tramadol
• Tranylcypromine
• Trazodone
• Triazolam
• Trifluoperazine
• Trifluperidol
• Triflupromazine
• Trimeprazine
• Trimipramine
• Tryptophan
• Venlafaxine
• Verapamil
• Vilazodone
• Voriconazole
• Vortioxetine
• Zaleplon
• Ziprasidone
• Zolmitriptan
• Zolpidem
• Zopiclone
• Zotepine
• Zuranolone

Using this medication with any of the complying with medications might cause a raised threat of specific negative effects, yet using both medications might be the very best treatment for you. If both medicines are recommended together, your doctor might alter the dosage or exactly how often you make use of one or both of the medicines.

• Acenocoumarol
• Carbamazepine
• Fosphenytoin
• Lixisenatide
• Phenytoin
• Warfarin
• Zidovudine

Interactions with Food/Tobacco/Alcohol

Specific medicines need to not be used at or around the moment of eating food or consuming certain sorts of food because interactions may occur. Using alcohol or tobacco with specific medicines might likewise cause communications to take place. The complying with communications have actually been chosen on the basis of their prospective value and are not always extensive.

Utilizing this medication with any of the adhering to is typically not recommended, yet might be unavoidable in some cases. If utilized with each other, your physician may transform the dose or how frequently you utilize this medicine, or give you special directions concerning using food, alcohol, or cigarette.

• Ethanol
• Grapefruit Juice
• Tobacco

Utilizing this medication with any of the following might trigger a raised risk of certain negative effects however may be inescapable sometimes. If used with each other, your doctor may alter the dose or just how frequently you utilize this medicine, or give you special instructions concerning using food, alcohol, or cigarette.

• Cabbage

Other Medical Problems

The visibility of various other clinical issues may influence the use of this medicine. Make sure you tell your doctor if you have any type of various other medical issues, particularly:

• Addison's disease (adrenal gland issue) or
• Alcohol abuse, background of or
• Brain lump, or background of or
• Breathing or lung issues (eg, asthma, apnea, COPD, emphysema, hypoxia) or
• Cor pulmonale (significant heart disease) or
• CNS depression or
• Drug dependence, particularly narcotic misuse or dependence, or background of or
• Enlarged prostate (BPH, prostatic hypertrophy) or
• Head injuries, or background of or
• Increased stress in the head or
• Hypothyroidism (an underactive thyroid) or
• Problems with passing urine-- Use with care. May increase danger for more significant side effects.

• Asthma, severe or extreme or
• Respiratory clinical depression (significant breathing issue) or
• Stomach or bowel clog (eg, paralytic ileus), understood or believed-- Should not be used in individuals with these conditions.

• Hypotension (low high blood pressure) or
• Pancreatitis (swelling of the pancreatic) or
• Seizures, history of-- Use with caution. May make these problems even worse.

• Kidney illness or
• Liver condition-- Use with care. The results may be raised because of slower elimination of the medicine from the body.

Along with its required results, a medication may create some undesirable effects. Although not every one of these adverse effects may happen, if they do happen they might need clinical interest.

Contact your doctor immediately if any one of the adhering to side effects take place:

More usual

• Dizziness
• lightheadedness

Occurrence not known

• Agitation
• back, leg, or stomach discomforts
• black, tarry stools
• hemorrhaging gums
• blistering, peeling off, or loosening of the skin
• blood in the urine or feceses
• blood in vomit
• blue lips or skin
• cools
• choking
• complication
• coughing
• dark urine
• dimming of the skin
• decline in the frequency of urination
• decrease in urine quantity
• diarrhea
• difficult or difficulty breathing
• trouble in passing pee (dribbling).
• trouble with ingesting.
• fainting.
• quickly heart beat.
• high temperature.
• high temperature with or without chills.
• basic body swelling.
• general feeling of tiredness or weak point.
• frustration.
• hoarseness.
• irregular, rapid or slow, or superficial breathing.
• joint or muscle mass pain.
• light-colored feceses.
• loss of appetite.
• lower back or side pain.
• mental depression.
• nausea.
• nosebleeds.
• not breathing.
• over active reflexes.
• painful or challenging peeing.
• pale or blue lips, finger nails, or skin.
• pinpoint red areas on the skin.
• poor sychronisation.
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue.
• red irritated eyes.
• red skin sores, typically with a purple facility.
• restlessness.
• serious or continuing tummy pain.
• shuddering.
• skin breakout, hives, or itching.
• aching throat.
• aching tongue.
• sores, ulcers, or white areas on the lips or in the mouth.
• sweating.
• speaking or acting with enjoyment you can not regulate.
• tightness in the chest.
• trembling or drinking.
• twitching.
• unable to talk.
• uncommon bleeding or bruising.
• unusual fatigue or weakness.
• upper best stomach or stomach pain.
• vomiting.
• yellow eyes and skin.

Obtain emergency situation assistance promptly if any one of the adhering to symptoms of overdose occur:.

Signs and symptoms of overdose.

• Bloody or gloomy pee.
• change in awareness.
• breast pain or pain.
• cold and clammy skin.
• coughing that in some cases generates a pink frothy spit.
• reduced recognition or responsiveness.
• difficult or difficulty breathing.
• extreme drowsiness.
• general feeling of discomfort or illness.
• raised sweating.
• uneven, fast or slow-moving, or shallow breathing.
• irregular heart beat.
• faintness, wooziness, or fainting.
• loss of awareness.
• no high blood pressure or pulse.
• no muscular tissue tone or movement.
• not breathing.
• pale or blue lips, finger nails, or skin.
• extreme drowsiness.
• slow or uneven heartbeat.
• quiting of heart.
• abrupt reduction in the quantity of pee.
• swelling in the legs and ankles.
• unpleasant breath odor.

Some negative effects might happen that usually do not require medical focus. These adverse effects might vanish throughout therapy as your body adjusts to the medicine. Additionally, your health care professional might have the ability to inform you regarding ways to stop or reduce some of these adverse effects. Check with your healthcare professional if any of the following side effects continue or are irritating or if you have any kind of questions about them:.

More common.

• Drowsiness.
• kicked back and calm feeling.
• sleepiness.

Incidence not understood.

• Belching.
• adjustments in state of mind.
• problem having a bowel movement.
• fear or anxiety.
• sensation of acid indigestion.
• hearing loss.
• damaged hearing.
• pain in the upper body listed below the breastbone.
• uncommon drowsiness, monotony, exhaustion, weakness, or feeling of sluggishness.

Other side impacts not provided might also occur in some patients. If you notice any various other impacts, consult your health care expert.

Call your medical professional for clinical recommendations regarding side effects. You might report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Anexsia.
• Ceta Plus.
• Co-Gesic.
• Dolorex Forte.
• Hycet.
• Lorcet.
• Lortab.
• Maxidone.
• Norco.
• Stagesic.
• Vicodin HP.
• Zydone.

Offered Dosage Forms:.

• Solution.
• Tablet.
• Elixir.

Restorative Class: Opioid/Acetaminophen Combination.

Chemical Class: Hydrocodone.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose. Large amounts of acetaminophen may cause liver damage.

It is very important that you understand the rules of the Opioid Analgesic REMS program to prevent addiction, abuse, and misuse of hydrocodone and acetaminophen combination. This medicine should also come with a Medication Guide and patient information leaflet. Read and follow these instructions carefully. Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions.

Measure the oral liquid with a marked measuring spoon, oral syringe, dropper, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

This combination medicine contains acetaminophen (Tylenol®). Carefully check the labels of all other medicines you are using, because they may also contain acetaminophen. It is not safe to use more than 4 grams (4,000 milligrams) of acetaminophen in one day (24 hours).

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For moderate to severe pain: For oral dosage form (capsules): Adults—1 or 2 capsules every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 8 capsules per day. Children—Use and dose must be determined by your doctor. For oral dosage form (elixir): Adults and children 14 years of age and older and weighing 46 kilograms (kg) and more—11.25 milliliters (mL) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 67.5 mL per day. Children 10 to 13 years of age and weighing 32 to 45 kg—7.5 mL every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 45 mL per day. Children 7 to 9 years of age and weighing 23 to 31 kg—5.6 mL every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 33.6 mL per day. Children 4 to 6 years of age and weighing 16 to 22 kg—3.75 mL every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 22.5 mL per day. Children 2 to 3 years of age and weighing 12 to 15 kg—2.8 mL every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 16.8 mL per day. Children younger than 2 years of age—Use and dose must be determined by your doctor. For oral dosage form (7.5 milligrams [mg] per 325 mg per 15 mL solution): Adults and children 14 years of age and older and weighing 46 kg and more—15 milliliters (mL) or 1 tablespoonful every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mL (6 tablespoonfuls) per day. Children 10 to 13 years of age and weighing 32 to 45 kg—10 mL (2 teaspoonfuls) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 60 mL (12 teaspoonfuls) per day. Children 7 to 9 years of age and weighing 23 to 31 kg—7.5 mL (1 and 1/2 teaspoonfuls) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 45 mL (9 teaspoonfuls) per day. Children 4 to 6 years of age and weighing 16 to 22 kg—5 mL (1 teaspoonful) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 30 mL (6 teaspoonfuls) per day. Children 2 to 3 years of age and weighing 12 to 15 kg—3.75 mL (3/4 teaspoonful) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 22.5 mL (4 and 1/2 teaspoonfuls) per day. Children younger than 2 years of age—Use and dose must be determined by your doctor. For oral dosage form (10 milligrams [mg] per 325 mg per 15 mL solution): Adults—15 milliliters (mL) or 1 tablespoonful every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mL (6 tablespoonfuls) per day. Children 14 years of age and older and weighing 46 kg and more—11.25 mL (2 and 1/4 teaspoonfuls) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 67.5 mL (13 and 1/2 teaspoonfuls) per day. Children 10 to 13 years of age and weighing 32 to 45 kg—7.5 mL (1 and 1/2 teaspoonfuls) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 45 mL (9 teaspoonfuls) per day. Children 7 to 9 years of age and weighing 23 to 31 kg—5.6 mL (1 teaspoonful) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 33.6 mL (6 and 1/2 teaspoonfuls) per day. Children 4 to 6 years of age and weighing 16 to 22 kg—3.75 mL (3/4 teaspoonful) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 22.5 mL (4 and 1/2 teaspoonfuls) per day. Children 2 to 3 years of age and weighing 12 to 15 kg—2.8 mL (1/2 teaspoonful) every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 16.8 mL (3 and 1/4 teaspoonfuls) per day. Children younger than 2 years of age—Use and dose must be determined by your doctor. For oral dosage form (5 milligrams [mg] per 325 mg tablets): Adults— Lortab®: 1 or 2 tablets every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 12 tablets per day. Norco® 5/325: 1 or 2 tablets every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 8 tablets per day. Generic: Dose depends on the strength of the tablet and must be determined by your doctor. Children—Use and dose must be determined by your doctor. For oral dosage form (7.5 mg per 325 mg tablets): Adults— Lortab®: 1 tablet every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 6 tablets per day. Norco® 7.5/325: 1 tablet every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 6 tablets per day. Generic: Dose depends on the strength of the tablet and must be determined by your doctor. Children—Use and dose must be determined by your doctor. For oral dosage form (10 mg per 325 mg tablets): Adults— Lortab®: 1 tablet every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 6 tablets per day. Norco® 10/325: 1 tablet every 4 to 6 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 6 tablets per day. Generic: Dose depends on the strength of the tablet and must be determined by your doctor. Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss a dose of hydrocodone and acetaminophen oral solution or Norco®, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Hydrocodone can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong narcotic pain medicines. Make sure you store the medicine in a safe and secure place to prevent others from getting it.

Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm.

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