Corticorelin ovine triflutate (Intravenous)

Corticorelin ovine triflutate injection is used in a test to find out if you have Cushing syndrome.

This medicine will be given by your doctor or under their supervision.

Your doctor will monitor your progress closely while you are taking this medicine. This will help your doctor see if the medicine is working properly and decide if you should continue. Blood tests may be necessary to check for side effects.

Allergic reactions may happen while you are taking this medicine. Inform your doctor immediately if you develop a rash or itchy skin, flushing or redness of the face, neck, and upper chest, large swelling like hives on the face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs, or if you have trouble breathing.

Do not take any other medicines unless your doctor has discussed them with you. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

In deciding to use a diagnostic test, any risks of the test must be weighed against the benefits it will provide. This is a decision you and your doctor will make together. Additionally, other factors may affect test results. For this test, consider the following:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also inform your healthcare professional if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not shown any pediatric-specific problems that would limit the usefulness of Acthrel® in children.

Geriatric

No information is available regarding how age affects the effects of Acthrel® in older patients.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if an interaction might occur. In these situations, your doctor may want to adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around mealtimes or with certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also cause interactions. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Difficult or labored breathing
• Feeling of warmth
• Hives or welts, itching, or skin rash
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Redness of the skin
• Redness of the face, neck, arms, and occasionally, upper chest
• Tightness in the chest

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Difficult or labored breathing
• Severe redness of the face

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Acthrel

A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.