Cystografin-Dilute (Intravenous)

Diatrizoate meglumine injection is used to help diagnose or locate issues in the urinary bladder. It is a radiopaque contrast agent. Contrast agents are used to create a clear image of different body parts during specific medical procedures, such as retrograde cystourethrography.

This medicine is to be used only by or under the direct supervision of a doctor.

Your doctor will monitor your progress closely while you are getting this medicine. This will help your doctor determine if the medicine is effective and if you should keep receiving it.

Serious reactions can happen while you are getting this medicine. Inform your doctor if you experience seizures, difficulty breathing, or chest tightness after receiving this medicine.

Before undergoing any medical tests, inform the medical doctor in charge that you are receiving this medicine. Some test results may be influenced by this medicine.

In deciding to use a medicine, you need to think about the risks versus the benefits. This is a choice you will make with your doctor. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

There is no information available on how diatrizoate meglumine injection affects children. Its safety and effectiveness have not been established.

Geriatric

There is no information available on how diatrizoate meglumine injection affects older adults.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the baby when used during breastfeeding.

Interactions with Medicines

Some medicines should not be taken together at all, while others may be used together even if an interaction might happen. In such cases, your doctor may adjust the dose or take other precautions. It is very important that your healthcare professional knows if you are taking any of the medicines listed below while receiving this medicine. The following interactions have been chosen for their potential importance and are not a complete list.

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you take one or both of the medicines.

• Propranolol

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around mealtime or with certain foods due to possible interactions. Drinking alcohol or using tobacco with certain medicines may also lead to interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical issues may affect how you can use this medicine. Make sure to tell your doctor if you have any other medical problems, especially:

• Allergy to iodine or other contrast agents, or history of
• Asthma, or history of—Use with caution. May increase the risk for more serious side effects.

• Urinary tract infection—Use with caution. May worsen this condition.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they might require medical attention.

Check with your doctor or nurse immediately if you experience any of the following side effects:

Incidence not known

• Blood in the urine
• Convulsions
• Cough
• Decrease in the amount of urine
• Difficulty with swallowing
• Dizziness
• Fast heartbeat
• Hives, itching, or rash
• Unable to pass urine
• Pain or burning while urinating
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Shortness of breath
• Tightness in the chest
• Unusual tiredness or weakness

Other side effects not listed may also happen in some patients. If you notice any other effects, consult your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Cystografin
• Cystografin-Dilute
• Hypaque-Cysto
• Hypaque Meglumine
• Reno-30
• Reno-60
• Reno-Dip

Available Dosage Forms:

• Solution

Therapeutic Class: Radiological Ionic Contrast Media

A doctor or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

Your doctor may give you a laxative the night before the test, and may recommend a low residue diet the day before the procedure.