Cystografin (Intravenous)

Diatrizoate meglumine injection is used to help diagnose or identify issues in the urinary bladder. It is a radiopaque contrast agent. Contrast agents are used to provide a clear image of various parts of the body during specific medical procedures, like retrograde cystourethrography.

This medicine should only be used by or under the direct supervision of a doctor.

Your doctor will monitor your progress closely while you are taking this medicine. This will help your doctor determine if the medicine is working correctly and whether you should keep taking it.

Serious reactions may happen while you are taking this medicine. Notify your doctor if you experience seizures, difficulty breathing, or chest tightness after taking this medicine.

Before undergoing any medical tests, inform the medical doctor in charge that you are taking this medicine. The results of some tests may be influenced by this medicine.

In deciding to use a medicine, you and your doctor need to consider the risks and benefits. For this medicine, keep the following in mind:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no information available on how diatrizoate meglumine injection affects children. Safety and effectiveness have not been established.

Geriatric

There is no information available on how diatrizoate meglumine injection affects older adults.

Breast Feeding

Research suggests that this medication poses minimal risk to infants when used by breastfeeding women.

Interactions with Medicines

Some medicines should not be used together, while others may be combined even if interactions could occur. If you are receiving this medicine, it is important for your healthcare professional to know if you are taking any of the following medicines. The following interactions are based on their potential significance and are not all-inclusive.

Using this medicine with the following medicine is usually not recommended, but may be necessary in some cases. If both are prescribed, your doctor may adjust the dose or frequency of one or both medicines.

• Propranolol

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around the time of eating food or certain types of food due to potential interactions. Drinking alcohol or using tobacco with some medicines may also lead to interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may affect the use of this medicine. Be sure to tell your doctor if you have any other medical conditions, especially:

• Allergy to iodine or other contrast agents, or history of
• Asthma, or history of—Use with caution. May increase risk of serious side effects.

• Urinary tract infection—Use with caution. May worsen this condition.

Along with its necessary effects, a medicine may cause some unwanted effects. Although not all of these side effects may happen, if they do occur, they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Blood in the urine
• convulsions
• cough
• decrease in the amount of urine
• difficulty with swallowing
• dizziness
• fast heartbeat
• hives, itching, or rash
• not able to pass urine
• pain or burning while urinating
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• shortness of breath
• tightness in the chest
• unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Cystografin
• Cystografin-Dilute
• Hypaque-Cysto
• Hypaque Meglumine
• Reno-30
• Reno-60
• Reno-Dip

Available Dosage Forms:

• Solution

Therapeutic Class: Radiological Ionic Contrast Media

A doctor or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

Your doctor may give you a laxative the night before the test, and may recommend a low residue diet the day before the procedure.