Ferric pyrophosphate

Ferric pyrophosphate is a product that provides iron. You usually get iron from the foods you eat. Iron helps your body make red blood cells, which transport oxygen throughout your blood to your tissues and organs.

Ferric pyrophosphate is used to treat iron deficiency in people with chronic kidney disease who are on dialysis.

Ferric pyrophosphate may also be used for reasons not mentioned in this medication guide.

Your doctor will do blood tests to ensure you do not have conditions that would make it unsafe for you to use ferric pyrophosphate.

Ferric pyrophosphate is added directly to the fluid in the dialyzer and is given during hemodialysis.

You will be monitored closely to ensure you do not have an allergic reaction.

A healthcare provider will give you this injection. Ferric pyrophosphate is not intended for use with home hemodialysis.

You will need regular medical tests.

You should not use ferric pyrophosphate if you have ever had a severe allergic reaction to any injected Iron products.

You should not use ferric pyrophosphate if you have ever had a severe allergic reaction to any injected iron product.

Tell your doctor if you have ever had:

• liver disease; or
• high blood pressure.

Ferric pyrophosphate may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine, and for at least 2 weeks after your last dose.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Get emergency medical help if you notice signs of an allergic reaction: hives; feeling light-headed; trouble breathing; swelling of your face, lips, tongue, or throat.

Ferric pyrophosphate may cause serious side effects. Call your doctor right away if you experience:

• bleeding around your dialysis vein access point;
• blue-colored skin, bulging purple-colored veins visible through your skin;
• swelling in your arms, legs, or fingers;
• unusual bleeding or bruising, coughing up blood;
• feeling light-headed, as if you might pass out;
• fever; or
• pain or burning when you urinate.

Common side effects of ferric pyrophosphate may include:

• headache, dizziness;
• swelling in your hands or feet;
• weakness, tiredness;
• muscle pain;
• feeling short of breath; or
• pain in your back, arms, or legs.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Usual Adult Dose for hemodialysis:

Add to bicarbonate concentrate for a 2 micromolar (110 mcg/L) concentration of iron (III) in the final hemodialysateComments:-This drug is not intended for use in peritoneal dialysis.-This drug has not been studied in home hemodialysis.Use: Replacement of iron to maintain hemoglobin in hemodialysis-dependent kidney disease (HDD-CKD)

Usual Adult Dose for Iron Deficiency:

Add to bicarbonate concentrate for a 2 micromolar (110 mcg/L) concentration of iron (III) in the final hemodialysateComments:-This drug is not intended for use in peritoneal dialysis.-This drug has not been studied in home hemodialysis.Use: Replacement of iron to maintain hemoglobin in hemodialysis-dependent kidney disease (HDD-CKD)

Because you will receive ferric pyrophosphate during your hemodialysis, it is unlikely that you will miss a dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Other drugs may affect ferric pyrophosphate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.