Ferric pyrophosphate citrate ()

Ferric pyrophosphate citrate is used as an iron replacement to prevent anemia in patients with chronic kidney disease who are on dialysis.

This medicine is available only with your doctor's prescription.

It is very important for your doctor to check your progress at regular visits to ensure this medicine is working properly and to look for any unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis requires immediate medical attention. Tell your doctor right away if you have a rash, itching, lightheadedness, dizziness, fainting, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are receiving this medicine.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to prevent pregnancy during therapy and for at least 2 weeks after the last dose. If you think you have become pregnant while using the medicine, tell your doctor right away.

In deciding to use a medicine, you and your doctor need to weigh the risks of taking it against the benefits it may provide. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Studies have not been done to determine how age affects the use of ferric pyrophosphate citrate in children. Safety and effectiveness have not been established.

Geriatric

Studies so far have not shown any specific problems in elderly patients that would limit the usefulness of ferric pyrophosphate citrate.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Weigh the potential benefits against the potential risks before using this medication during breastfeeding.

Interactions with Medicines

Some medicines should not be taken together at all, while in some cases, two different medicines can be used together even if there is a chance of interaction. In these situations, your doctor may need to adjust the dose, or other precautions may be necessary. It is particularly important for your healthcare professional to know if you are taking any of the medicines listed below while receiving this medicine. The following interactions have been chosen based on their potential significance and may not include all possible interactions.

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or frequency of one or both medicines.

• Baloxavir Marboxil
• Bictegravir
• Dimercaprol
• Eltrombopag
• Erdafitinib
• Magnesium Sulfate
• Raltegravir

Using this medicine with any of the following medicines may increase the risk of certain side effects, but using both may be the best option for you. If both medicines are prescribed together, your doctor may adjust the dose or frequency of one or both medicines.

• Delafloxacin
• Minocycline
• Zinc

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around the time of eating food or certain types of food due to potential interactions. Using alcohol or tobacco with some medicines can also cause interactions. The following interactions have been selected based on their potential significance and may not include all possible interactions.

Using this medicine with any of the following may increase the risk of certain side effects, but may be unavoidable in some situations. If used together, your doctor may adjust the dose or frequency of this medicine or provide specific instructions regarding the use of food, alcohol, or tobacco.

• Phytic Acid Containing Food

Along with its necessary effects, this medicine may cause some unwanted effects. Not all of these side effects may occur, but if they do, they may need medical attention.

Check with your doctor or nurse right away if any of the following side effects happen:

More common

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• blurred vision
• confusion
• dizziness, faintness, or lightheadedness when getting up suddenly from lying or sitting
• rapid weight gain
• sweating
• tingling of the hands or feet
• trouble breathing
• unusual tiredness or weakness
• unusual weight gain or loss

Less common

• Bladder pain
• bloody or cloudy urine
• difficult, burning, or painful urination
• fever
• frequent urge to urinate
• lower back or side pain

Incidence not known

• Cough
• difficulty with breathing or swallowing
• hives, itching, or skin rash
• nausea
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• reddening of the skin, especially around the ears
• swelling of the eyes, face, or inside of the nose
• tightness in the chest

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

More common

• Headache
• muscle spasms
• pain in the arms or legs

Less common

• Back pain
• lack or loss of strength

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

In the U.S.

• Triferic

Available Dosage Forms:

• Powder for Solution
• Solution

Therapeutic Class: Iron Supplement

A doctor or other healthcare professional will give you this medicine in a dialysis clinic or hospital. This medicine is added to the dialysis solution.