Floxin (Otic)

Ofloxacin is an antibiotic. Ofloxacin otic solution is used to treat infections in the ear canal. It is also used to treat middle ear infections in patients who have nonintact tympanic membranes (holes or tubes in the eardrums).

You can only get this medicine with a prescription from your doctor.

If your symptoms do not improve within a few days, or if they get worse, contact your doctor.

Oral and systemic ofloxacin and other similar antibiotics have sometimes led to a severe allergic reaction. It is not known if otic ofloxacin may cause this reaction. However, stop using this medicine and contact your doctor right away if you notice a skin rash or itching, shortness of breath, or swelling of the face or neck.

In deciding to use a medicine, the risks of taking it must be weighed against the benefits it will provide. This is a choice you and your doctor will make together. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, tell your healthcare professional about any other allergies you have, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Use is not recommended in infants younger than 1 year of age.

Geriatric

Many medicines have not been studied specifically in older adults. Therefore, it may not be clear whether they work the same way they do in younger adults or if they cause different side effects or issues in older adults. There is no specific information comparing the use of otic ofloxacin in elderly patients with use in other age groups.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Consider the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

While some medicines should not be used together at all, in other cases, two different medicines may be used together even if an interaction might occur. In such cases, your doctor may want to adjust the dose, or other precautions may be necessary. When taking this medicine, it is particularly important that your healthcare professional knows if you are taking any of the medicines listed below. The following interactions have been chosen based on their potential significance and are not necessarily exhaustive.

Using this medicine with any of the following medicines is not recommended. Your doctor may choose not to treat you with this medication or change some of the other medicines you take.

• Bepridil
• Cisapride
• Dronedarone
• Levoketoconazole
• Mesoridazine
• Pimozide
• Piperaquine
• Saquinavir
• Sparfloxacin
• Terfenadine
• Thioridazine
• Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or how often you use one or both of the medicines.

• Acarbose
• Acecainide
• Adagrasib
• Albiglutide
• Alfuzosin
• Alogliptin
• Alosetron
• Amiodarone
• Amisulpride
• Amitriptyline
• Amoxapine
• Anagrelide
• Apomorphine
• Aripiprazole
• Aripiprazole Lauroxil
• Arsenic Trioxide
• Asenapine
• Astemizole
• Atazanavir
• Azimilide
• Azithromycin
• Bedaquiline
• Betamethasone
• Bretylium
• Budesonide
• Buprenorphine
• Bupropion
• Buserelin
• Canagliflozin
• Ceritinib
• Chloroquine
• Chlorpromazine
• Chlorpropamide
• Cholera Vaccine, Live
• Ciprofloxacin
• Citalopram
• Clarithromycin
• Clofazimine
• Clomipramine
• Clothiapine
• Clozapine
• Corticotropin
• Cortisone
• Cosyntropin
• Crizotinib
• Cyclobenzaprine
• Dabrafenib
• Dapagliflozin
• Dasatinib
• Deflazacort
• Degarelix
• Delamanid
• Desipramine
• Deslorelin
• Deutetrabenazine
• Dexamethasone
• Dexmedetomidine
• Disopyramide
• Dofetilide
• Dolasetron
• Domperidone
• Donepezil
• Droperidol
• Dulaglutide
• Efavirenz
• Empagliflozin
• Encorafenib
• Entrectinib
• Ertugliflozin
• Erythromycin
• Escitalopram
• Etrasimod
• Exenatide
• Fexinidazole
• Fingolimod
• Flecainide
• Fluconazole
• Fludrocortisone
• Fluocortolone
• Fluoxetine
• Formoterol
• Foscarnet
• Fostemsavir
• Gatifloxacin
• Gemifloxacin
• Gepirone
• Glasdegib
• Glimepiride
• Glipizide
• Glyburide
• Gonadorelin
• Goserelin
• Granisetron
• Halofantrine
• Haloperidol
• Histrelin
• Hydrocortisone
• Hydroxychloroquine
• Hydroxyzine
• Ibutilide
• Iloperidone
• Imipramine
• Inotuzumab Ozogamicin
• Insulin
• Insulin Aspart, Recombinant
• Insulin Bovine
• Insulin Degludec
• Insulin Detemir
• Insulin Glulisine
• Insulin Lispro, Recombinant
• Ivosidenib
• Ketoconazole
• Lapatinib
• Lefamulin
• Lenvatinib
• Leuprolide
• Levofloxacin
• Linagliptin
• Liraglutide
• Lixisenatide
• Lofexidine
• Lopinavir
• Lumefantrine
• Macimorelin
• Magnesium Sulfate
• Mefloquine
• Metformin
• Methadone
• Methylprednisolone
• Metronidazole
• Mifepristone
• Miglitol
• Mirtazapine
• Mobocertinib
• Moricizine
• Moxifloxacin
• Nafarelin
• Nateglinide
• Nilotinib
• Norfloxacin
• Nortriptyline
• Octreotide
• Olanzapine
• Ondansetron
• Osilodrostat
• Osimertinib
• Oxaliplatin
• Ozanimod
• Pacritinib
• Paliperidone
• Panobinostat
• Paroxetine
• Pasireotide
• Pazopanib
• Phenobarbital
• Pimavanserin
• Pioglitazone
• Pitolisant
• Ponesimod
• Porfimer
• Posaconazole
• Pramlintide
• Prednisolone
• Prednisone
• Primidone
• Procainamide
• Prochlorperazine
• Promethazine
• Protriptyline
• Quetiapine
• Quinidine
• Quinine
• Quizartinib
• Ranolazine
• Rasagiline
• Relugolix
• Repaglinide
• Ribociclib
• Rosiglitazone
• Saxagliptin
• Selpercatinib
• Semaglutide
• Sematilide
• Sertraline
• Sevoflurane
• Siponimod
• Sitagliptin
• Sodium Phosphate
• Sodium Phosphate, Dibasic
• Sodium Phosphate, Monobasic
• Solifenacin
• Sorafenib
• Sotalol
• Sulpiride
• Sunitinib
• Tacrolimus
• Tedisamil
• Telithromycin
• Tetrabenazine
• Tizanidine
• Tolazamide
• Tolbutamide
• Toremifene
• Trazodone
• Triamcinolone
• Triclabendazole
• Trifluoperazine
• Trimipramine
• Triptorelin
• Vandetanib
• Vardenafil
• Vemurafenib
• Vilanterol
• Vinflunine
• Voclosporin
• Voglibose
• Voriconazole
• Warfarin
• Zuclopenthixol

Using this medicine with any of the following medicines may increase the risk of certain side effects, but using both medications may be the best treatment for you. If both medicines are prescribed together, your doctor may adjust the dose or how often you use one or both of the medicines.

• Aminolevulinic Acid
• Didanosine
• Lanthanum Carbonate

Interactions with Food/Tobacco/Alcohol

Some medicines should not be used at or around the time of eating food or certain types of food, as interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Along with its needed effects, Floxin (Otic) may cause some unwanted effects. Although not all of these side effects may happen, if they do, they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Burning, itching, redness, skin rash, swelling, or other signs of irritation not present before using this medicine

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

• Dizziness

Rare

• Bleeding from the ear
• Fast heartbeat
• Fever
• Headache
• Ringing in the ear
• Runny or stuffy nose
• Sore throat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Change in taste
• Earache
• Numbness or tingling

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Floxin

Available Dosage Forms:

• Solution

Therapeutic Class: Antibacterial

Chemical Class: Fluoroquinolone

Ofloxacin eardrops comes with patient information and instructions (Medication Guide). Be sure to read these instructions before using the eardrops. If you have any questions, check with your doctor or health care professional.

To use:

• Hold the bottle in your hands for 1 or 2 minutes to warm up the solution before putting it in your ear. Otherwise, putting cold solution in your ear could cause you to become dizzy.
• Wash your hands with soap and water.
• Gently clean any discharge that can be removed easily from the outer ear, but do not insert any object or swab into the ear canal.
• If you are using the eardrops for a middle ear infection—Drop the medicine into the ear canal. Then, gently press the tragus of the ear (see the diagram in the Medication Guide) four times in a pumping motion. This will allow the drops to pass through the hole or tube in the eardrum and into the middle ear.
• If you are using the eardrops for an ear canal infection—Gently pull the outer ear up and back for adults (down and back for children) to straighten the ear canal. This will allow the eardrops to flow down into the ear canal.
• Keep the ear facing up for about 5 minutes to allow the medicine to come into contact with the infection.
• If both ears are being treated, turn over after 5 minutes, and repeat the application for the other ear.
• To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the ear). Also, keep the container tightly closed.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For eardrops dosage form: For ear infections: Adults and teenagers (12 years of age and older)—Place 10 drops in each affected ear two times a day for ten to fourteen days, depending on the infection. Children 1 to 12 years of age—Place 5 drops in each affected ear two times a day for ten days. Children younger than 1 year of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.