Fluorescein (Intravenous)

Fluorescein injection helps make specific parts of the eye, like the retina and iris, more visible during eye medical procedures.

This medicine should only be given by your doctor or under their direct supervision.

Your doctor will monitor your progress closely while you or your child is receiving this medicine. This helps your doctor determine if the medicine is effective and if you should continue treatment, as well as check for any unwanted effects.

This medicine may cause a serious allergic reaction called anaphylaxis. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, or fainting. Other signs may include changes in the skin color of the face, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swelling of the eyelids or around the eyes. If these side effects occur, seek emergency help right away.

Tell your doctor immediately if you or your child experiences redness, swelling, or peeling of the skin, or severe pain or loss of feeling in the arm for several hours after receiving this medicine.

Inform your doctor if you or your child has nausea, vomiting, diarrhea, or stomach pain after receiving this medicine.

You or your child may notice a strong taste in your mouth after this medicine is injected. Your skin may have a yellowish tint for about 6 to 12 hours after your test. Your urine may appear bright yellow for up to 36 hours after your test.

In deciding to use a medicine, you and your doctor need to think about the risks and benefits. For this medicine, consider the following:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also inform your healthcare professional if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies so far have not shown any specific problems in children that would limit the use of fluorescein injection.

Geriatric

Studies so far have not shown any specific problems in older adults that would limit the use of fluorescein injection.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while others can be used together with caution. In these cases, your doctor may want to adjust the dose, or take other precautions. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around mealtime or with certain foods due to potential interactions. Using alcohol or tobacco with certain medicines may also cause interactions. Discuss with your healthcare professional how to use your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical issues may affect how this medicine works for you. Make sure to tell your doctor if you have any other medical problems, especially:

• Allergy to food, dye, or medicine, history of or
• Asthma, or history of—May increase the risk of having an allergic reaction occur again.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may happen, if they do, they may require medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare

• Bluish color
• cold, clammy skin
• confusion
• cough
• difficulty breathing
• difficulty swallowing
• dizziness
• fast heartbeat
• hives, itching, or skin rash
• lightheadedness
• noisy breathing
• pain, redness, swelling, or peeling of the skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• severe pain in the arm
• sweating
• tightness in the chest
• unconsciousness
• unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Abdominal or stomach pain
• diarrhea
• nausea
• vomiting
• yellow skin and urine

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• AK-Fluor
• Angioscein
• Fluorescite

Available Dosage Forms:

• Solution

Therapeutic Class: Disclosing Agent

A nurse or other trained health professional will give you or your child this medicine in a hospital. This medicine is given through a needle placed in one of your veins.