Fluorescite (Intravenous)

Fluorescein injection is used to make certain parts of the eye (for example, the retina and iris) easier to see during eye medical procedures.

This medicine should only be given by your doctor or under their direct supervision.

Your doctor will closely monitor your progress while you or your child is receiving this medicine. This helps your doctor determine if the medicine is effective and if you should continue treatment, as well as checking for side effects.

This medicine may cause a serious allergic reaction called anaphylaxis. Anaphylaxis needs immediate medical attention. The most serious signs of this reaction include very fast or irregular breathing, gasping for breath, or fainting. Other signs may include changes in the skin color of the face, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swelling of the eyelids or around the eyes. If any of these side effects happen, seek emergency help immediately.

Inform your doctor right away if you or your child experiences redness, swelling, or peeling of the skin, or severe pain or loss of feeling in the arm for several hours after receiving this medicine.

Let your doctor know if you or your child has nausea, vomiting, diarrhea, or stomach pain after receiving this medicine.

You or your child may notice a strong taste in your mouth after this medicine is injected. Your skin may have a yellowish color for about 6 to 12 hours after your test. Your urine may appear bright yellow for up to 36 hours after your test.

In deciding to use a medicine, you and your doctor will consider the risks of taking the medicine against the benefits it may provide. For this medicine, keep the following in mind:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you may have, including those to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Current studies have not shown any pediatric-specific problems that would limit the usefulness of fluorescein injection in children.

Geriatric

Current studies have not shown any geriatric-specific problems that would limit the usefulness of fluorescein injection in the elderly.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Consider the potential benefits and risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should never be used together, while in other cases two different medicines may be used together despite possible interactions. In these situations, your doctor may want to adjust the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicines.

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional how your medicine interacts with food, alcohol, or tobacco.

Other Medical Problems

Having other medical issues may affect how this medicine works for you. Make sure to inform your doctor if you have any other medical conditions, especially:

• Allergy to food, dye, or medicine, history of
• Asthma, or history of—May increase the risk of having an allergic reaction again.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may happen, if they do, they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare

• Bluish color
• cold, clammy skin
• confusion
• cough
• difficulty breathing
• difficulty swallowing
• dizziness
• fast heartbeat
• hives, itching, or skin rash
• lightheadedness
• noisy breathing
• pain, redness, swelling, or peeling of the skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• severe pain in the arm
• sweating
• tightness in the chest
• unconsciousness
• unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Abdominal or stomach pain
• diarrhea
• nausea
• vomiting
• yellow skin and urine

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• AK-Fluor
• Angioscein
• Fluorescite

Available Dosage Forms:

• Solution

Therapeutic Class: Disclosing Agent

A nurse or other trained health professional will give you or your child this medicine in a hospital. This medicine is given through a needle placed in one of your veins.