Hyoscyamine and phenyltoloxamine

Hyoscyamine and phenyltoloxamine is a combination medicine that treats indigestion (upset stomach, gas, bloating) and lowers stomach acid.

Hyoscyamine and phenyltoloxamine may also be used for other reasons not mentioned in this medication guide.

Follow all instructions on your prescription label and read any medication guides or instruction sheets. Use the medicine exactly as directed.

Take with food.

If you break or open a hyoscyamine and phenyltoloxamine capsule, do not inhale the powder inside the capsule.

Store at room temperature, away from moisture, heat, and light.

You should not use hyoscyamine and phenyltoloxamine if you have severe ulcerative colitis, or if you are unable to urinate.

Before you take hyoscyamine and phenyltoloxamine, tell your doctor if you have glaucoma, asthma, heart disease, high blood pressure, coronary artery disease, or a thyroid disorder.

You should not use this medicine if you are allergic to hyoscyamine or phenyltoloxamine, or if:

• you have severe ulcerative colitis; or
• you are unable to urinate.

You may not be able to take this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma, heart disease, high blood pressure, coronary artery disease, or a thyroid disorder.

Tell your doctor if you have or have had:

• a bladder obstruction or other urination problems;
• an enlarged prostate;
• ulcerative colitis;
• glaucoma;
• myasthenia gravis;
• liver or kidney disease;
• heart problems; or
• breathing problems.

Tell your doctor if you are pregnant or breastfeeding.

Do not give this medicine to a child without medical advice.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Hyoscyamine and phenyltoloxamine may cause serious side effects. Stop using hyoscyamine and phenyltoloxamine and call your doctor right away if you have:

• pounding heartbeats or fluttering in your chest;
• severe stomach cramps or constipation;
• little or no urination;
• confusion, memory problems, slurred speech;
• diarrhea; or
• problems with balance or muscle movement.

Side effects such as dry mouth, constipation, and confusion may happen more often in older adults.

Common side effects of hyoscyamine and phenyltoloxamine may include:

• dizziness, drowsiness;
• constipation;
• decreased sweating, decreased urination;
• dry mouth;
• blurred vision; or
• impotence, loss of interest in sex, or trouble having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Take your dose as soon as you can, but only if you are about to eat a meal. If you miss a meal, skip the missed dose and wait until your next meal.

Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Avoid taking hyoscyamine and phenyltoloxamine at the same time you take an antacid. Antacids can make it harder for your body to absorb hyoscyamine and phenyltoloxamine. You may take the antacid after you have taken hyoscyamine and phenyltoloxamine and eaten a meal.

Drinking alcohol with this medicine can cause side effects.

This medicine may cause blurred vision and may impair your reactions. Avoid driving or doing dangerous activities until you know how this medicine will affect you.

Avoid becoming overheated or dehydrated during exercise and in hot weather. This medicine can decrease sweating, and you may be more likely to experience heat stroke.

Using hyoscyamine and phenyltoloxamine with other medicines that cause drowsiness can make you feel even sleepier. Check with your doctor before taking opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Inform your doctor about all the other medicines you are taking, especially:

• medicine for depression, anxiety, mood disorders, or mental illness;
• cold or allergy medicine (such as Benadryl);
• medicine for Parkinson's disease;
• medicine for stomach issues, motion sickness, or irritable bowel syndrome;
• medicine for an overactive bladder; or
• asthma medication that opens the airways (bronchodilators).

This list is not complete. Other medicines may interact with hyoscyamine and phenyltoloxamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are mentioned here.