MPI MAA (Intravenous)

Technetium Tc 99m albumin aggregated injection helps your doctor take images of your lungs to check for lung problems in both children and adults. It is also used to help your doctor view an image of your peritoneovenous [LeVeen] shunt.

Technetium Tc 99m albumin aggregated injection is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that can be used to identify and treat certain diseases or to examine how the body's organs work.

This medicine can only be given by or under the direct supervision of a doctor who has specialized training in nuclear medicine.

It is very important that your doctor closely monitors you or your child while receiving this medicine. This allows your doctor to see if the medicine is working properly and to decide if you or your child should keep using it.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and need immediate medical help. Contact your doctor right away if you have a rash, itching, swelling of the face, tongue, or throat, trouble breathing, or chest pain after the injection.

You will be exposed to radiation when you receive this medicine. Discuss any concerns you have with your doctor.

In deciding to use a diagnostic test, you and your doctor need to consider the risks of the test against its benefits. Other factors may also affect the test results. For this test, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Studies have not shown any specific problems in children that would limit the usefulness of Technetium Tc 99m albumin aggregated injection.

Geriatric

Studies have not been done to see how age affects the use of technetium Tc 99m albumin aggregated injection in elderly patients. However, older patients are more likely to have liver, kidney, or heart issues related to age, which may require caution when using this medicine.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Weigh the potential benefits against the potential risks before using this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together. In other situations, two different medicines may be used together even if there is a potential interaction. In these cases, your doctor may adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken around mealtimes or with certain types of food due to possible interactions. Using alcohol or tobacco with some medicines may also lead to interactions. Discuss with your healthcare professional how to take your medicine in relation to food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may affect the use of this diagnostic test. Be sure to tell your doctor if you have any other medical problems, especially:

• Allergy to human serum albumin, history of or
• Pulmonary hypertension (severe increased blood pressure in the lungs)—Should not be used in patients with these conditions.

• Blood circulation problems or
• Cor pulmonale (serious heart condition) or
• Heart problems (e.g., right-to-left heart shunts)—Use with caution. May worsen these conditions.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may happen, if they do, they may need medical attention.

Check with your doctor or nurse right away if any of the following side effects happen:

Incidence not known

• Chest pain or tightness
• Confusion
• Cough
• Difficulty swallowing
• Dizziness
• Faintness
• Fast heartbeat
• Fever and chills
• Hives, itching, skin rash
• Hoarseness
• Irritation
• Joint pain, stiffness, or swelling
• Nausea
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Redness of the skin
• Sweating
• Swelling of the eyelids, face, lips, hands, or feet
• Trouble breathing or swallowing

Some side effects may happen that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also happen in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• MPI MAA
• Pulmolite
• Technescan MAA

Available Dosage Forms:

• Kit

Therapeutic Class: Diagnostic Agent, Radiopharmaceutical Imaging

A doctor or other trained health professional will give you or your child this medicine. This medicine is given through a needle placed in one of your veins before you have a scan.

You will need to urinate right away after your exam and as often as you can for the first hours after you receive this medicine. Drink plenty of fluids before and after you receive this medicine so you will pass more urine. This will help flush the medicine from your body.