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Persantine

Generic name: dipyridamole (oral/injection)

Last updated November 3, 2026 0 views
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What is Persantine?

Persantine oral is used to stop blood clots from forming after heart valve replacement surgery.

Persantine injection is used in a test that measures how well your heart is pumping blood. This is sometimes referred to as a "stress test."

Persantine may also be used for other reasons that are not mentioned in this medication guide.

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How should I take Persantine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may change your dose from time to time. Use the medicine exactly as directed.

Persantine oral is taken by mouth, sometimes along with other medications to prevent blood clots. Use all medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice.

You may need frequent medical tests.

Store at room temperature, away from moisture and heat.

Persantine injection is given as an infusion into a vein. A healthcare provider will administer this medicine and other injected medicines during your stress test.

If you need a stress test while taking Persantine by mouth, you may need to stop taking it 48 hours before your stress test. Follow all instructions on how to prepare for this test.

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Warnings

Follow all directions on your medicine label and package. Inform each of your healthcare providers about all your medical conditions, allergies, and all medicines you take.

This section was rewritten for readability and reviewed for meaning.

`What should I discuss with my healthcare provider before taking Persantine?

You should not use Persantine if you are allergic to it.

Tell your doctor if you have ever had:

  • coronary artery disease (hardened arteries);
  • a heart attack;
  • uncontrolled chest pain (angina);
  • myasthenia gravis;
  • low blood pressure; or
  • liver disease.

Before you have a stress test with Persantine injection: Tell your doctor if you already take this medicine by mouth, or if you take an asthma medicine called theophylline.

Tell your doctor if you are pregnant or breastfeeding.

Persantine oral is not approved for use by anyone younger than 12 years old. This medicine injection is used only in adults.

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Persantine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Persantine may cause serious side effects. Call your doctor immediately if you experience:

  • a light-headed feeling, as if you might faint;
  • chest pain; or
  • liver problems--upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Older adults may be more likely to feel light-headed while using Persantine.

Common side effects of Persantine may include:

  • headache;
  • dizziness;
  • rash; or
  • upset stomach.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is close to the time for your next dose. Do not take two doses at once.

Persantine injection is used as a single dose and does not have a daily dosing schedule.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include flushing (warmth, redness, or tingly feeling), feeling restless, sweating, weakness, or fainting.

Ask a doctor or pharmacist before using aspirin or any medicines for pain, fever, swelling, or cold/flu symptoms.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

For 24 hours before a stress test: Your doctor may tell you to avoid certain foods or drinks that contain caffeine (such as coffee, tea, energy drinks, chocolate). Follow these instructions carefully to avoid your test having to be postponed or cancelled.

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What other drugs will affect Persantine?

Tell your doctor about all your other medicines, especially:

  • medicine to treat Parkinson's disease; or
  • medicine to treat dementia or symptoms of Alzheimer's disease.

This list is not complete. Other drugs may affect Persantine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.