Phytonadione (oral/injection)

Phytonadione is a synthetic version of vitamin K, which is found naturally in the body.

Phytonadione is used to treat vitamin K deficiency and to address specific bleeding or blood-clotting issues caused by other medications or medical conditions.

Phytonadione may also be used for reasons not mentioned in this medication guide.

Never use phytonadione in larger amounts, or for longer than recommended by your doctor.

A phytonadione injection may cause a serious allergic reaction. Tell your caregiver if you feel weak, tingly, light-headed, warm, itchy, or if you have chest pain, trouble breathing, a cold sweat, or swelling in your face.

You should not use phytonadione if you are allergic to it.

Tell your doctor if you have ever had liver disease.

Phytonadione injection may contain an ingredient that can cause serious side effects or death in very young or premature babies. Do not give phytonadione to a child without medical advice.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

A phytonadione injection may cause a serious allergic reaction. Tell your caregiver if you feel weak, tingly, light-headed, warm, itchy, or if you have chest pain, trouble breathing, cold sweat, or swelling in your face.

Phytonadione may cause serious side effects. Call your doctor immediately if you have:

• an unusual or unpleasant taste in your mouth;
• a light-headed feeling, like you might faint;
• blue-colored lips;
• jaundice (yellowing of the skin or eyes);
• trouble breathing;
• a weak but rapid pulse; or
• skin redness, itching, or a hard lump where the injection was given.

Common side effects of phytonadione may include:

• dizziness;
• flushing (warmth, redness, or tingly feeling);
• changes in your sense of taste;
• sweating; or
• pain or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Never use phytonadione in larger amounts, or for longer than prescribed.

A phytonadione injection is given into a muscle, under the skin, or as an infusion into a vein. A healthcare provider will give the injection.

You may need frequent blood tests.

If you need surgery or dental work, tell the surgeon or dentist you currently use this medicine.

Store at room temperature away from moisture and heat. Protect from light. Keep the medicine in the original container and tightly closed when not in use.

Call your doctor for guidance if you miss a dose of phytonadione.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Tell your doctor about all the other medicines you are taking. Some may influence phytonadione, particularly:

• a blood thinner--warfarin, Coumadin, Jantoven, or others.

This list is not complete. Other drugs may influence phytonadione, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are mentioned here.