Propantheline

Propantheline is used to help treat a peptic ulcer.

Propantheline may also be used for reasons not mentioned in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may sometimes change your dose. Use the medicine exactly as directed.

Propantheline is usually taken 3 or 4 times a day, 30 minutes before meals and at bedtime. Follow your doctor's instructions.

Store propantheline at room temperature away from moisture and heat.

You should not take propantheline if you have glaucoma, myasthenia gravis, a blockage in your stomach or intestines, a bladder obstruction, severe ulcerative colitis, or toxic megacolon.

You should not take propantheline if you are allergic to it, or if you have:

• a stomach or bowel obstruction (including paralytic ileus);
• glaucoma;
• a bladder obstruction or other urination problems;
• severe constipation;
• severe ulcerative colitis or toxic megacolon;
• active bleeding with fast heartbeats, low blood pressure, shortness of breath, and cold hands or feet; or
• myasthenia gravis.

Tell your doctor if you have ever had:

• a nerve-muscle disorder;
• heart disease, or a heart rhythm disorder;
• high blood pressure;
• an intestinal disorder such as ulcerative colitis;
• liver or kidney disease;
• hiatal hernia or reflux esophagitis (GERD);
• a thyroid disorder; or
• a colostomy or ileostomy.

Tell your doctor if you are pregnant or breast-feeding.

Older adults may be more sensitive to the effects of this medicine.

Propantheline is not approved for use by anyone younger than 18 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Propantheline may cause serious side effects. Stop using propantheline and call your doctor right away if you have:

• diarrhea;
• fast or pounding heartbeats, fluttering in your chest;
• eye pain or redness, seeing halos around lights;
• painful or difficult urination; or
• little or no urination.

Common side effects of propantheline may include:

• dry mouth, nose, or throat;
• blurred vision;
• constipation;
• headache, dizziness, drowsiness;
• confusion or feeling nervous;
• decreased sweating;
• nausea, vomiting, bloating;
• decreased sense of taste;
• impotence, sexual problems; or
• sleep problems (insomnia).

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Peptic Ulcer:

Initial dose: 15 mg orally 30 minutes before each meal AND 30 mg orally at bedtimeComments:-The initial daily dose is 75 mg.-Dose adjustments should be determined by the patient's age and tolerance.-This drug should be used with caution in older patients.Use: Adjunctive treatment of peptic ulcers

Take the medicine as soon as you can, but skip the missed dose if it is nearly time for your next dose. Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling restless or excited, warmth or tingling under your skin, confusion, unusual thoughts or behavior, muscle weakness, or paralysis.

Avoid driving or hazardous activity until you know how propantheline will affect you. Your reactions could be impaired.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Propantheline can decrease perspiration and you may be more prone to heat stroke.

Using propantheline with other medications that cause drowsiness can make this effect worse. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Propantheline slows down the digestive system, which can make it harder for your body to absorb any medicines taken by mouth. Inform your doctor if any of your oral medications do not seem to work as well while you are using propantheline.

Tell your doctor about all your current medications. Many drugs can affect propantheline, especially:

• heart rhythm medication;
• medicine to treat depression, anxiety, mood disorders, or mental illness;
• cold or allergy medicine (Benadryl and others);
• medicine to treat Parkinson's disease;
• steroid medication;
• medicine to treat stomach issues, motion sickness, or irritable bowel syndrome;
• medicine to treat overactive bladder; or
• bronchodilator asthma medication.

This list is not complete and many other drugs may affect propantheline. This includes prescription and over-the-counter medications, vitamins, and herbal products. Not all possible drug interactions are included here.