Technetium tc 99m exametazime (Injection)

Technetium Tc 99m exametazime (Injection) is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that can be used to find and treat certain diseases or to study how the body's organs are working.

Technetium Tc 99m exametazime (Injection) helps your doctor see images of your brain to check its function. It is used for cerebral perfusion scintigraphy in stroke. This medicine is also used for leukocyte labeled scintigraphy to locate stomach infections and inflammatory bowel disease.

This medicine must be given only by or under the direct supervision of a doctor who has specialized training in nuclear medicine.

It is very important that your doctor checks you closely while you are receiving this medicine. This will help your doctor see if the medicine is working properly and decide if you should keep receiving it.

This medicine may cause serious allergic reactions. Contact your doctor immediately if you experience a rash, itching, swelling of the face, tongue, and throat, trouble breathing, or chest pain after you receive the injection.

You will be exposed to radiation when you are given this medicine. Discuss any concerns you have about this with your doctor.

In deciding to use a medicine, you and your doctor will need to weigh the risks against the benefits. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, tell your healthcare professional about any other allergies you may have, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Studies have not been conducted to determine how age affects the use of technetium Tc 99m exametazime injection in children. Safety and effectiveness have not been established for this age group.

Geriatric

While studies on how age affects the use of technetium Tc 99m exametazime injection in older adults have not been done, no specific problems related to older patients have been reported so far. However, older patients may have kidney issues related to aging, which could require caution and a dose adjustment for those receiving technetium Tc 99m exametazime injection.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Consider the potential benefits and risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together, even if interactions might occur. In these situations, your doctor may need to adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used around mealtimes or with specific foods due to possible interactions. Using alcohol or tobacco with some medicines may also lead to interactions. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical conditions may influence the use of this medicine. Make sure to inform your doctor if you have any other medical issues, especially:

• Kidney disease—Use with caution. The effects may be stronger due to slower removal of the medicine from the body.

• Stomach problems (e.g., peritonitis) or
• Tumor—Use with caution. Test results may be impacted in patients with these conditions.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may require medical attention.

Check with your doctor or nurse right away if any of the following side effects occur:

Rare

• Fever
• flushing or redness of the skin
• rash
• swelling or puffiness of the face
• unusually warm skin

Other side effects not listed may also happen in some patients. If you notice any other effects, talk to your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Ceretec
• Drax Exametazime

Available Dosage Forms:

• Kit

Therapeutic Class: Diagnostic Agent, Radiopharmaceutical Imaging

A doctor or other health professional will give you this medicine. This medicine is given through a needle placed in a vein.

You will need to urinate right away and as often as possible after receiving this medicine. Drink plenty of fluids before and after receiving this medicine so you will pass more urine.