Technetium tc 99m oxidronate (Injection)

Technetium Tc 99m oxidronate (Injection) is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that can be used to find and treat certain diseases or to examine how the body's organs are working.

Technetium Tc 99m oxidronate (Injection) is used to help your doctor see an image of your bones to assist in diagnosing bone issues.

This medicine should only be given by or under the direct supervision of a doctor who has specialized training in nuclear medicine.

It is very important that your doctor monitors you closely while you are receiving this medicine. This will help your doctor determine if the medicine is effective and decide if you should keep receiving it.

You will be exposed to radiation when you are given this medicine. Discuss any concerns you have about this with your doctor.

In deciding to use a medicine, you and your doctor need to weigh the risks of taking the medicine against the benefits it may provide. Here are some important points to consider for this medicine:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies conducted so far have not shown specific problems in children that would limit the usefulness of technetium Tc 99m oxidronate injection.

Geriatric

There is no information available on how age affects the effects of technetium Tc 99m oxidronate injection in older patients.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Consider the potential benefits against the potential risks before using this medication while breastfeeding.

Interactions with Medicines

Some medicines should never be used together, while others may be used together even if there is a chance of interaction. In such cases, your doctor may adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken at or around mealtime, or in conjunction with certain foods, as interactions may occur. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical issues, especially:

• Alkalosis—May increase the risk for hypocalcemia.

• Hypocalcemia (low calcium levels)—Use with caution, as it may worsen this condition.

• Kidney disease—Use with caution, as the effects may be stronger due to slower elimination of the medicine from the body.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Difficulty with breathing or swallowing
• fever
• hives
• nausea
• reddening of the skin, especially around the ears
• swelling of the eyes, face, or inside of the nose
• unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Technescan HDP

A doctor or other health professional will give you this medicine. This medicine is given through a needle placed in a vein.

You should urinate right away and as often as possible for 4 to 6 hours after receiving this medicine. Drink plenty of fluids before and after receiving this medicine so you will pass more urine.