Diatrizoate (Intravenous)

Diatrizoate meglumine injection is used to help diagnose or identify issues in the urinary bladder. It is a radiopaque contrast agent. Contrast agents are used to provide a clear image of various parts of the body during specific medical procedures, like retrograde cystourethrography.

This medicine is to be used only by or under the direct supervision of a doctor.

Your doctor will monitor your progress closely while you are receiving this medicine. This will help your doctor determine if the medicine is working correctly and if you should keep receiving it.

Severe reactions may happen while you are receiving this medicine. Inform your doctor if you experience seizures, difficulty breathing, or tightness in the chest after receiving this medicine.

Before undergoing any medical tests, inform the medical doctor in charge that you are receiving this medicine. The results of some tests may be influenced by this medicine.

In deciding to use a medicine, you and your doctor need to think about the risks and benefits. Here are some important things to consider for this medicine:

Allergies

Let your doctor know if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also inform your health care professional about any other allergies you may have, like to foods, dyes, preservatives, or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatric

There is no information available on how diatrizoate meglumine injection affects children. Its safety and effectiveness have not been established.

Geriatric

There is no information available on how diatrizoate meglumine injection affects older adults.

Breast Feeding

Studies suggest that this medication poses minimal risk to infants when used during breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while others may be used together with caution. If you are receiving this medicine, it's important for your healthcare professional to know if you are taking any of the medicines listed below. The following interactions are significant and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or how often you use one or both of the medicines.

• Propranolol

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also cause interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical problems may affect how you can use this medicine. Make sure to inform your doctor if you have any other medical conditions, especially:

• Allergy to iodine or other contrast agents, or history of
• Asthma, or history of—Use with caution. May increase the risk of more serious side effects.

• Urinary tract infection—Use with caution. May worsen this condition.

Along with its necessary effects, this medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may require medical attention.

Check with your doctor or nurse right away if any of the following side effects occur:

Incidence not known

• Blood in the urine
• convulsions
• cough
• decrease in the amount of urine
• difficulty with swallowing
• dizziness
• fast heartbeat
• hives, itching, or rash
• unable to pass urine
• pain or burning while urinating
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• shortness of breath
• tightness in the chest
• unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Cystografin
• Cystografin-Dilute
• Hypaque-Cysto
• Hypaque Meglumine
• Reno-30
• Reno-60
• Reno-Dip

Available Dosage Forms:

• Solution

Therapeutic Class: Radiological Ionic Contrast Media

A doctor or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

Your doctor may give you a laxative the night before the test, and may recommend a low residue diet the day before the procedure.