Hymovis

Hymovis is like the fluid that is found around your joints. This fluid helps to lubricate and absorb shock in the joints.

Hymovis is used to relieve knee pain caused by osteoarthritis.

Hymovis is typically given after other arthritis medications have been tried and did not work.

Hymovis may also be used for reasons that are not mentioned in this medication guide.

You should not receive Hymovis if you have a bleeding disorder, certain allergies, or an infection in your knee or in the skin around your knee.

You should not be treated with Hymovis if you are allergic to it, or if you have:

• an allergy to gram positive bacteria proteins (ask your doctor if you are not sure);
• a bleeding or blood clotting disorder such as hemophilia; or
• an infection in your knee or in the skin around your knee.

It is not known whether Hymovis will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using Hymovis.

It is not known whether hyaluronan passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Hymovis is not approved for use by anyone younger than 21 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Hymovis may cause serious side effects. Call your doctor right away if you have:

• bleeding;
• increased knee pain; or
• signs of infection (warmth, swelling, redness) around your knee.

Common side effects of Hymovis may include:

• joint pain, stiffness, or swelling;
• itching, numbness, or tingling;
• headache, dizziness;
• back pain;
• swelling, pain, redness, or mild discomfort where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Hymovis is injected directly into your knee joint. A healthcare provider will give you this injection.

You may be given more than one Hymovis injection. If so, additional injections are usually given at least 1 week after your first injection.

Follow your doctor's dosing instructions very carefully.

This medicine should give you relief from pain for several months.

Tell your doctor if your symptoms do not improve, or if they get worse.

Since Hymovis is usually given in a single dose, it does not have a daily dosing schedule.

If you need to receive more than one Hymovis injection, call your doctor for instructions if you miss your next injection appointment.

Since Hymovis is administered by a healthcare professional in a medical setting, it is unlikely that an overdose will happen.

For at least 48 hours after your injection: Do not jog, engage in strenuous activity, or participate in high-impact sports such as tennis. Also, avoid weight-bearing activities or standing for more than 1 hour at a time.

Other drugs may interact with hyaluronan, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform each of your health care providers about all medicines you are currently using and any medicine you begin or discontinue.