Hypaque-Cysto (Intravenous)

Diatrizoate meglumine injection is used to help diagnose or find problems in the urinary bladder. It is a radiopaque contrast agent. Contrast agents are used to create a clear picture of the different parts of the body during certain medical procedures, such as retrograde cystourethrography.

This medicine is to be used only by or under the direct supervision of a doctor.

Your doctor will monitor your progress closely while you are taking this medicine. This helps your doctor determine if the medicine is effective and if you should keep receiving it.

Severe reactions can happen while you are taking this medicine. Inform your doctor if you experience seizures, difficulty breathing, or chest tightness after taking it.

Before undergoing any medical tests, inform the medical doctor in charge that you are taking this medicine. Some test results may be influenced by this medicine.

In deciding to use a medicine, you and your doctor need to consider the risks and benefits. The following points should be taken into account for this medicine:

Allergies

Inform your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you may have, such as to foods, dyes, preservatives, or animals. For over-the-counter products, carefully read the label or package ingredients.

Pediatric

There is no information available about how diatrizoate meglumine injection affects children. Safety and effectiveness have not been established.

Geriatric

There is no information available about how diatrizoate meglumine injection affects older adults.

Breast Feeding

Studies suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Some medicines should not be used together, while others may be combined even if an interaction could happen. In these cases, your doctor might adjust the dose or take other precautions. It is especially important for your healthcare professional to know if you are taking any of the medicines listed below while receiving this medicine. The following interactions have been chosen based on their potential importance and may not include all possible interactions.

Using this medicine with any of the following medicines is generally not recommended, but may be necessary in some situations. If both medicines are prescribed, your doctor may alter the dose or frequency for one or both medicines.

• Propranolol

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken around the time of eating or with particular types of food because interactions may occur. Using alcohol or tobacco with specific medicines may also lead to interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical issues may impact the use of this medicine. Be sure to inform your doctor if you have any other medical problems, especially:

• Allergy to iodine or other contrast agents, or a history of
• Asthma, or a history of—Use with caution. May increase the risk of more serious side effects.

• Urinary tract infection—Use with caution. May worsen this condition.

Along with its needed effects, a medicine may cause some unwanted effects. Not all of these side effects may occur, but if they do, they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Blood in the urine
• convulsions
• cough
• decrease in the amount of urine
• difficulty with swallowing
• dizziness
• fast heartbeat
• hives, itching, or rash
• not able to pass urine
• pain or burning while urinating
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• shortness of breath
• tightness in the chest
• unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Cystografin
• Cystografin-Dilute
• Hypaque-Cysto
• Hypaque Meglumine
• Reno-30
• Reno-60
• Reno-Dip

Available Dosage Forms:

• Solution

Therapeutic Class: Radiological Ionic Contrast Media

A doctor or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

Your doctor may give you a laxative the night before the test, and may recommend a low residue diet the day before the procedure.