Monovisc

Monovisc is like the fluid that surrounds the joints in your body. This fluid helps to lubricate and absorb shock for the joints.

Monovisc is used to treat knee pain caused by osteoarthritis.

Monovisc is typically given after other arthritis medications have been tried without success.

Monovisc may also be used for reasons not mentioned in this medication guide.

You should not receive Monovisc if you have a bleeding disorder, specific allergies, or an infection in your knee or in the skin around your knee.

You should not be treated with Monovisc if you are allergic to it, or if you have:

• an allergy to gram positive bacteria proteins (ask your doctor if you are not sure);
• a bleeding or blood clotting disorder such as hemophilia; or
• an infection in your knee or in the skin around your knee.

It is not known whether Monovisc will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using Monovisc.

It is not known whether hyaluronan passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Monovisc is not approved for use by anyone younger than 21 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Monovisc may cause serious side effects. Call your doctor right away if you have:

• bleeding;
• increased knee pain; or
• signs of infection (warmth, swelling, redness) around your knee.

Common side effects of Monovisc may include:

• joint pain, stiffness, or swelling;
• itching, numbness, or tingling;
• headache, dizziness;
• back pain;
• swelling, pain, redness, or mild discomfort where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Monovisc is injected directly into your knee joint. A healthcare provider will give you this injection.

You may be given more than one Monovisc injection. If so, additional injections are usually given at least 1 week after your first injection.

Follow your doctor's dosing instructions very carefully.

This medicine should give you relief from pain for several months.

Tell your doctor if your symptoms do not improve, or if they get worse.

Since Monovisc is typically administered in a single dose, there is no daily dosing schedule.

If you need more than one Monovisc injection, contact your doctor for guidance if you miss your next injection appointment.

Since Monovisc is administered by a healthcare professional in a medical setting, an overdose is unlikely to happen.

For at least 48 hours after your injection: Avoid jogging, strenuous activity, or high-impact sports like tennis. Also, do not engage in weight-bearing activities or stand for more than 1 hour at a time.

Other drugs may interact with hyaluronan, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform all of your health care providers about all medicines you are currently using and any medicine you begin or stop using.