Triluron (injection)

Triluron is similar to the fluid that surrounds your joints. This fluid helps to lubricate and cushion the joints.

Triluron is used to relieve knee pain from osteoarthritis.

Triluron is typically given when other arthritis medications have not worked.

Triluron may also be used for reasons not mentioned in this medication guide.

You do not receive a Triluron if you have an infection in your knee or in the skin around your knee.

You should not receive Triluron if you are allergic to it, or if you have an infection in your knee or in the skin around your knee.

Triluron is not approved for use by anyone younger than 21 years old.

Tell your doctor if you have ever had:

• blood clots or circulation problems in your legs; or
• an allergy to birds, feathers, or egg products.

It is not known whether Triluron will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Triluron may cause serious side effects. Call your doctor right away if you have:

• severe pain or swelling around the knee after the injection.

Common side effects of Triluron may include:

• warmth, pain, redness, stiffness, bruising, or swelling where the medicine was injected;
• nausea, stomach pain;
• trouble walking;
• swelling in your hands or feet;
• back pain, joint pain, muscle pain;
• numbness or tingling;
• headache, dizziness; or
• runny or stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Triluron is injected directly into your knee joint. A healthcare provider will give you this injection.

Triluron is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully.

To prevent pain and swelling, your doctor may recommend resting your knee or applying ice for a short time after your injection.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Tell your doctor if your symptoms do not improve, or if they get worse.

Call your doctor for guidance if you miss an appointment for your Triluron injection.

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely.

For at least 48 hours after your injection, do not jog, do strenuous activity, or participate in high-impact sports such as soccer or tennis. Also, do not do weight-bearing activity or stand for longer than 1 hour at a time. Ask your doctor how long to wait before you can resume these activities.

Other drugs may affect Triluron, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor about all your current medicines and any medicine you begin or stop using.